Results 191 to 200 of about 41,384 (251)

Development of a digitalised complex intervention to promote activity of older people in rural areas: study protocol of a feasibility study. [PDF]

Pilot Feasibility Stud
Beutner K, Lamprecht J, Roggendorf S, Aßmann P, Hübner G, Steckelberg A, Schmidt H.   +6 more
europepmc   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

The "Lower Is Better" Debate in Hypertension Management: A Narrative Review of Divergent Recommendations in the 2024 ESC and 2025 ACC/AHA Guidelines. [PDF]

Cureus
Vijaykumar V.
europepmc   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Impact of prior SARS-CoV-2 acquisition on binding and neutralizing antibody responses following COVID-19 vaccination: A cross-protocol analysis of individual-level data from six phase 3 clinical trials. [PDF]

Vaccine
Hudson A, Borgetti S, Rick AM, Laurens MB, Robinson ST, Gay CL, Baden LR, Goepfert PA, Rouphael N, El Sahly HM, Gray GE, Grinsztejn B, Sobieszczyk ME, Falsey AR, Huang Y, Janes H, Follmann D, Koup RA, Priddy F, Hendriks J, Shoemaker K, Dunkle LM, de Bruyn G, Devlin L, Neuzil KM, Kublin JG, Corey L, Walsh SR, Kotloff KL, Gilbert PB.   +29 more
europepmc   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

Advanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho, Hyunjae Kim, Seung Eun Yu, Sangmin Lee, Ji Youn Lee, Mi‐Lan Kang, Kang Suk Lee, Young Sik Choi, Hak‐Joon Sung   +8 more
wiley   +1 more source

Multifactorial strategies for the prevention of the risks of ulceration in patients affected by diabetic foot: a no-profit, multicentre, clinical trial protocol. [PDF]

BMJ Open
Leardini A, Pagotto U, Dalla Paola L, Leopardi MP, Belvedere C, Ortolani M, Platano D, Caravaggi P, Rogati G, Sacchetti G, Grimaldi MS, Casadei G, Lopreiato V, Tremoli E, Maffessanti F, Tenti E, Sangiorgi D, Ferroni L, Malagoni AM, Veglia F, Berti L.   +20 more
europepmc   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Fluconazole plus flucytosine versus fluconazole alone for adults with HIV-associated cryptococcal antigenaemia identified through screening: a multi-centre phase III randomised-controlled trial. [PDF]

Trials
Murphy K, Nel JS, Moosa MY, Wilson DP, Tsitsi M, Mfinanga S, Kivuyo S, Kyazze D, Alam N, Meintjes G, Eriksson M, Adams J, Menezes C, Variava E, Black J, Bremer M, Dat VQ, Le T, Schutz C, Loyse A, Wake RM, Lawrence DS, Wang D, Jaffar S, Jarvis JN, Harrison TS, Molloy SF, Govender NP.   +27 more
europepmc   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source