Results 51 to 60 of about 1,453,806 (248)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Do clinicians and clinical researchers do enough to foster social inclusion? [PDF]

open access: yes, 2015
Purpose – The purpose of this paper is to raise questions about the social issues involved in mental and physical health. It highlights how, even where social issues are evident, clinicians and clinical researchers often focus mainly on individual ...
Holttum, S.
core   +1 more source

Mammographic interpretation in Vietnam: Tailored educational strategies are needed to increase clinicians’ expertise

open access: yes, 2021
Aim Breast cancer incidence is rapidly increasing throughout South East Asia, highlighting the need for high-quality early diagnosis and treatment. This study aims to investigate the efficacy of mammography detection in Hanoi and Ho Chi Minh City (HCMC),
Felix Caspar   +33 more
core   +1 more source

The prevention and treatment of opportunistic infections in HIV-infected adults

open access: yesSouth African Family Practice, 2003
A number of lengthy and comprehensive articles and guidelines exist with regard to the treatment and prevention of opportunistic infections, but this guidelines is designed to be easy and simple for a practitioner to use.
G. Maartens
doaj   +1 more source

Letter to the editor on “Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017, parts 1–3”

open access: yesArchives of Public Health, 2022
We would like to thank authors Reece and Hulse (2022) for their three-part article titled “Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer ...
Frank Yizhao Chen   +2 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Engaging clinicians in research: barriers, benefits and building a blueprint

open access: yes, 2023
Implications for practice and research:Leadership action by prioritising clinical research activities and introducing a range of clinician engagement strategies for research can lead to better staff retention and patient care.Implementation of clinician ...
Mickan, Sharon, Mickan, S, Sharon Mickan
core   +1 more source

Management of Tuberculosis: a handbook for clinicians [PDF]

open access: yes, 2012
This handbook, a distillation of recommendations from international TB guidelines and the accumulated clinical experience of its authors, provides practical information for clinicians involved in the care of patients with tuberculosis (TB) and other ...
Street, Alan   +3 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

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