Sarcomatoid salivary duct carcinoma of parotid gland – a rare histological variant
Salivary duct carcinoma (SDC) is a rare and high-grade malignant tumor that arises predominantly in a major salivary gland and bears a striking histological resemblance to high grade ductal adenocarcinoma of breast.
Nitish Virmani +2 more
doaj +4 more sources
Animal models of NASH: getting both pathology and metabolic context right [PDF]
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core +1 more source
BackgroundHepatocellular carcinoma (HCC) represents a complex ailment characterized by an unfavorable prognosis in advanced stages. The involvement of immune cells in HCC progression is of significant importance.
Dengyong Zhang +9 more
doaj +1 more source
Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas [PDF]
Background Piwi-interacting RNAs (piRNAs) are small RNAs of 27–30 nucleotides mapping to transposons or clustering in repeat genomic regions. Preliminary studies suggest an important role in cancerogenesis. This study is the first one investigating their
Busch, Jonas +8 more
core +2 more sources
Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer [PDF]
Introduction Aromatase inhibitors (AIs) are a vital component of estrogen receptor positive (ER+) breast cancer treatment. De novo and acquired resistance, however, is common.
A Mackay +65 more
core +3 more sources
Predictive Biomarkers for Response and Toxicity of Induction Chemotherapy in Head and Neck Cancers
This review focuses on the molecular biology of head and neck squamous cell carcinomas and presents current and emerging biomarkers of the response of patients to induction chemotherapy.
Łukasz Boguszewicz
doaj +1 more source
Adjuvant chemotherapy and survival among patients 70 years of age and younger with node-negative breast cancer and the 21-gene recurrence score of 26-30 [PDF]
BACKGROUND: The benefits of chemotherapy in node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients with the 21-gene recurrence score (RS) of 18-30, particularly those with RS 26-30 ...
Cho, Young Up +9 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi +10 more
wiley +1 more source
Clinicopathological Conference: Complications of Rheumatoid Arthritis [PDF]
Clinicopathlogical conference transcript from the Medical College of Virginia. Discussants include P. Franklin Mullinax and R.
Hudson, R. Page, Jr. +1 more
core +1 more source

