Results 1 to 10 of about 1,252,032 (285)

Validation of the International Tumor Budding Consensus Conference 2016 recommendations on tumor budding in stage I-IV colorectal cancer [PDF]

Human Pathology, 2019
Tumor budding is a robust prognostic parameter in colorectal cancer and can be used as an additional factor to guide patient management. Although backed by large bodies of data, a standardized scoring method is essential for integrating tumor budding in reporting protocols.
Inti Zlobec, Peter Studer, Heather Dawson   +2 more
exaly   +7 more sources

Tumor budding in laryngeal carcinoma

Indian Journal of Pathology and Microbiology, 2019
Background: Tumor budding was defined as a single cancer cell or a cluster of fewer than five cancer cells in the stroma of the invasive tumor margin. It has been suggested as a prognostic factor in various cancers, such as esophageal, lung, colorectal ...
Sumeyye Ekmekci, Ulku Kucuk, Seda Kokkoz, Ebru Cakir, Murat Gumussoy   +4 more
doaj   +4 more sources

Tumor budding in invasive breast cancer - An indispensable budding touchstone

Indian Journal of Pathology and Microbiology, 2020
Background: Tumor budding denotes a phenomenon in which the tumor cells, singly or in small aggregates, become detached from the neoplastic glands at the invasive front of adenocarcinoma.
B N Kumarguru, Anikode S Ramaswamy, Shahanuma Shaik, Aruna Karri, Venugopal Sandeep Srinivas, B M Prashant   +5 more
doaj   +3 more sources

Histopathologic Features of the Tumor Budding in Adenocarcinoma of the Lung: Tumor Budding As an Index to Predict the Potential Aggressiveness [PDF]

Journal of Thoracic Oncology, 2010
The term tumor budding has been applied to single cells or small clusters of up to four cells within the stromal tissue at the invasive margin of colorectal cancers. This morphologic feature is increasingly being recognized as an adverse prognostic factor.
Atsushi Ochiai, Hajime Ōtsuka, Yutaka Nishiwaki   +2 more
exaly   +3 more sources

PD-L1 expression patterns in stage IB1 cervical squamous cell carcinoma: a retrospective study on implications for tumor budding and immune microenvironment [PDF]

PeerJ
Background The immune microenvironment at the tumor invasion front plays a pivotal role in cancer progression. Tumor budding, an aggressive histopathological feature, has been linked to poor outcomes in various malignancies.
Shanming Lu, Kun Liu, Wenjuan Luo, Shaoqiu Zheng   +3 more
doaj   +3 more sources

Pathological and Clinical Significance of Tumor Budding and Its Association with Epithelial-Mesenchymal Transition in Colorectal Carcinoma: A Retrospective Observational Study [PDF]

Iranian Journal of Medical Sciences
Background: Metastases, not the primary tumor, account for most cancer-related deaths. Tumor budding, thought to represent epithelial-mesenchymal transition (EMT), has garnered attention due to its association with invasion and migration. This study aims
Bashar Al Hassawi
doaj   +2 more sources

Exploratory analysis of tumor budding density in resected synchronous and metachronous colorectal liver metastases [PDF]

Frontiers in Oncology
BackgroundTumor budding is an adverse histopathological feature in colorectal cancer, but its role in colorectal liver metastases (CRLM) remains insufficiently defined.
Nemanja Petrović, Nemanja Petrović, Biljana Kukić, Biljana Kukić, Nenad Šolajić, Nenad Šolajić, Nemanja Maletin, Nemanja Maletin, Ivana Kolarov Bjelobrk, Ivana Kolarov Bjelobrk, Jelena Radić, Jelena Radić, Aleksandar Đermanović, Aleksandar Đermanović, Ivan Nikolić, Ivan Nikolić   +15 more
doaj   +2 more sources

Advancing Tumor Budding Detection With Fourier Ptychography Microscopy. [PDF]

Cancer Med
ABSTRACTBackgroundTumor budding is an independent predictor of metastasis and prognosis in colorectal cancer and is a vital part of the pathology specification report. In a conventional pathological section observation process, pathologists have to repeatedly switch from 10× objective to 20× objective several times to localize and image the target ...
Su Y, Sun R, Wang Y, Xi Y, Zhang S.
europepmc   +5 more sources

Tumor budding in colorectal carcinoma: time to take notice [PDF]

Modern Pathology, 2012
Tumor 'budding', loosely defined by the presence of individual cells and small clusters of tumor cells at the invasive front of carcinomas, has received much recent attention, particularly in the setting of colorectal carcinoma. It has been postulated to represent an epithelial-mesenchymal transition.
Richard Kirsch, Robert Riddell, Bojana Mitrović   +2 more
exaly   +3 more sources

Associations of Biomarkers of Systemic Inflammation, Angiogenesis, and Cell‐to‐Cell Adhesion With Tumor Budding Among Early‐Onset and Later‐Onset Colorectal Cancer Patients [PDF]

Cancer Medicine
Background High tumor budding and elevated systemic inflammation are adverse prognostic indicators in colorectal cancer. Its underlying mechanisms remain poorly understood.
Oda Hausmann, Pauline P. Schobert, Jennifer Ose, Caroline Himbert, Maria Pletneva, Jolanta Jedrzkiewicz, Anne Nguyen, Tengda Lin, Christy A. Warby, Sheetal Hardikar, Anita R. Peoples, Ildiko Strehli, Lyen C. Huang, Jessica N. Cohan, Bartley Pickron, Courtney Scaife, Christopher I. Li, William M. Grady, David Shibata, Adetunji T. Toriola, Martin Schneider, Jane C. Figueiredo, Erin M. Siegel, Biljana Gigic, Stephan Herzig, Mmadili N. Ilozumba, Cornelia M. Ulrich   +26 more
doaj   +2 more sources