Results 11 to 20 of about 1,252,032 (285)

Tumor Budding in Upper Gastrointestinal Carcinomas [PDF]

Frontiers in Oncology, 2014
The basis of personalized medicine in oncology is the prediction of an individual’s risk of relapse and death from disease. The presence of tumor budding (TB) at the tumor–host interface of gastrointestinal cancers has been recognized as a hallmark of unfavorable disease biology. TB is defined as the presence of dedifferentiated cells or small clusters
Koelzer, Viktor H, Langer, Rupert, Zlobec, Inti, Lugli, Alessandro   +3 more
openaire   +8 more sources

Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016 [PDF]

Modern Pathology, 2017
Tumor budding is a well-established independent prognostic factor in colorectal cancer but a standardized method for its assessment has been lacking. The primary aim of the International Tumor Budding Consensus Conference (ITBCC) was to reach agreement on an international, evidence-based standardized scoring system for tumor budding in colorectal ...
Lugli, A, Kirsch, R, Ajioka, Y, Bosman, F, Cathomas, G, Dawson, H, El Zimaity, H, Fléjou, J-F, Hansen, TP, Hartmann, A, Kakar, S, Langner, C, Nagtegaal, I, Puppa, G, Riddell, R, Ristimäki, A, Sheahan, K, Smyrk, T, Sugihara, K, Terris, B, Ueno, H, Vieth, M, Zlobec, I, Quirke, P   +23 more
core   +12 more sources

Tumor Budding and Prognosis in Gastric Adenocarcinoma [PDF]

American Journal of Surgical Pathology, 2019
Tumor budding has been associated with poor prognosis in several cancer types, but its significance in gastric cancer is unknown. The aim of this study was to assess the prognostic significance of tumor budding in gastric adenocarcinoma, and its main histologic types.
Kemi, N. (Niko), Eskuri, M. (Maarit), Ikäläinen, J. (Julia), Karttunen, T. J. (Tuomo J.), Kauppila, J. H. (Joonas H.)   +4 more
core   +6 more sources

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget

Oncotarget, 2010
Epithelial mesenchymal transition (EMT) is proposed as a critical mechanism for the acquisition of malignant phenotypes by epithelial cells. In colorectal cancer, tumor cells having undergone EMT are histologically represented by the presence of tumor buds defined as single cells or small clusters of de-differentiated tumor cells at the invasive front.
Zlobec, Inti, Lugli, Alessandro
core   +6 more sources

Evaluation of Tumor Budding in Primary Colorectal Cancer and Corresponding Liver Metastases Based on H&E and Pancytokeratin Staining [PDF]

Frontiers in Medicine, 2019
In colorectal cancer, tumor budding is associated with tumor progression and represents an additional prognostic factor in the TNM classification.
Annika Blank, Carla Schenker, Heather Dawson, Guido Beldi, Inti Zlobec, Alessandro Lugli   +5 more
doaj   +3 more sources

Molecular and Pathogenetic Aspects of Tumor Budding in Colorectal Cancer [PDF]

Frontiers in Medicine, 2015
In recent years, tumor budding in colorectal cancer has gained much attention as an indicator of lymph node metastasis, distant metastatic disease, local recurrence, worse overall and disease-free survival, and as an independent prognostic factor. Tumor buds, defined as the presence of single tumor cells or small clusters of up to five tumor cells at ...
Dawson H, Lugli A
openaire   +7 more sources

Prognostic Impact of Tumor Budding on Moroccan Gastric Cancer Patients

Clinical Pathology, 2023
Background: Tumor budding (TB) has been defined as an independent prognostic factor in many carcinomas like colon adenocarcinoma, but its prognostic impact on gastric cancer patients remains not well established.
Souhaila El Yaagoubi, Meryem Zaryouhi, Soumaya Benmaamar, Fatima El Agy, Layla Tahiri El Ousrouti, Nawal Hammas, Hicham El Bouhaddouti, Zineb Benbrahim, Nada Lahmidani, Laila Chbani   +9 more
doaj   +2 more sources

Correlation Between Tumor Budding and Survivin Expression in Colorectal Cancer [PDF]

Clinical and Experimental Gastroenterology
Guangping Zhang, Qingzhong Min Department of Pathology, Ya’an People’s Hospital, Ya’an, Sichuan, People’s Republic of ChinaCorrespondence: Qingzhong Min, Department of Pathology, Ya’an People’s Hospital, Ya’an, Sichuan, People’s Republic of China, Tel ...
Zhang G, Min Q
doaj   +1 more source

Combined Model of Tumor–Stroma Ratio and Tumor Budding Are Not Associated with Tumor Recurrence or Metastasis in Oral Squamous Cell Carcinoma Patients [PDF]

Diagnostics
Histopathological grading of oral squamous cell carcinoma is currently based on differentiation of cells, while additional histological parameters, such as the tumor–stroma ratio (TSR), tumor budding (TB), or the combined TSR/tumor budding model could ...
Drago Boščić, Emili Dragaš, Andro Košec, Goran Geber, Čedna Tomasović-Lončarić, Davor Vagić   +5 more
doaj   +2 more sources

Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma

Zhongliu Fangzhi Yanjiu, 2021
Objective To investigate the clinical pathological significance of tumor budding in T1 stage esophageal squamous cell carcinoma. Methods Tumor budding was searched for in the resected tissues of T1 stage esophageal squamous cell carcinoma(ESCC), and the ...
WANG Kang, YANG Chun
doaj   +1 more source