Establishing cost-effectiveness of genetic targeting of cancer therapies [PDF]
The clinical benefit of a new genomic instrument, the 70-gene signature for breast cancer patients, is being evaluated in a randomised clinical trial. The early, controlled implementation process is supported by a Constructive Technology Assessment to ...
Harten, W.H. van +3 more
core +1 more source
Epidemiology, impact and control of rabies in Nepal : a systematic review [PDF]
Background: Rabies is a vaccine-preventable viral zoonosis belonging to the group of neglected tropical diseases. Exposure to a rabid animal may result in a fatal acute encephalitis if effective post-exposure prophylaxis is not provided.
Ale, Anita +13 more
core +4 more sources
Bona Fide Intersegmental Plane Hepatectomy Along the Glissonean Branches (BIPHG)
ABSTRACT This review traces the author's personal journey over three decades in the evolution of liver resection techniques, culminating in the proposal of the Bona Fide Intersegmental Plane Hepatectomy Along Glissonean Branches (BIPHG). Beginning with pioneering experiences in laparoscopic and robotic liver surgeries, the author highlights key ...
Go Wakabayashi, Taiga Wakabayashi
wiley +1 more source
Unilocular radiolucency of mandibular angle region –a clinicopathological conference
Calcifying Cystic Odontogenic Tumor (CCOT) constitutes 1% of all jaw cysts and considered as one of the rarest odontogenic lesions. It's a group of odontogenic entities which exhibits variety of clinical and biological behaviors.
Anil Mangutti +3 more
doaj
Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study. [PDF]
Background Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus ...
Baeten, Kurt +19 more
core +1 more source
In this retrospective cohort of 3487 patients with CRC, history of CCY was associated with significantly worse prognosis in patients with proximal CRC but not in those with distal CRC. This differential prognostic impact showed a statistically significant interaction between tumor location and history of CCY and remained robust after PSM.
Masashi Tsunematsu +9 more
wiley +1 more source
Interpretable classification of Alzheimer's disease pathologies with a convolutional neural network pipeline. [PDF]
Neuropathologists assess vast brain areas to identify diverse and subtly-differentiated morphologies. Standard semi-quantitative scoring approaches, however, are coarse-grained and lack precise neuroanatomic localization.
Beckett, Laurel +6 more
core
Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin +12 more
core +1 more source
BEV-IP : perioperative chemotherapy with bevacizumab in patients undergoing cytoreduction and intraperitoneal chemoperfusion for colorectal carcinomatosis [PDF]
Background: Selected patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) benefit from cytoreductive surgery (CRS) combined with intraperitoneal chemoperfusion (IPC).
Ceelen, Wim +3 more
core +2 more sources
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood +6 more
wiley +1 more source

