Results 161 to 170 of about 93,827 (314)

Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction

Advanced Science, EarlyView.
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen, Guancen Lin, Chuan‐Shen Hu, Yong Wang   +3 more
wiley   +1 more source

A comparative study of the risk of delayed cerebral ischemia after clipping and coiling of ruptured intracranial aneurysms: a systematic review and meta-analysis. [PDF]

Front Neurol
Jiang C, Peng J, Luo T, Huang M, Chen A, Xu J, Xiong W, Tan Z, Su J.   +8 more
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

[Clipping: Eight Hopeful Congressmen]

, 1943
Newspaper clipping featuring several articles including an article titled, “Eight Hopeful Congressmen”, “Hitler’s Subtlest Poison”, and “The Red Star Rises”.
Rovere, Richard H.
core  

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

Advanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang, Zhihan Zhou, Qipeng Xie, Zheng Wang, Lijiong He, Yutong Liu, Lijuan Huang, Liuxian Ye, Limeng Hu, Baokun Li, Yang Wang, Xiaohui Hua, Xuelei Liu, Yunping Zhao, Jingxia Li, Jinfei Chen, Guiying Wang, Xian Shen, Wei Chen, Chuanshu Huang   +19 more
wiley   +1 more source

The Defense Responses of <i>Eucalyptus</i> to Insect-Feeding and Leaf-Clipping Stresses. [PDF]

Life (Basel)
Chen C, Zhang Z, Lin W, Xu M, Lin Z, Zheng K, Ailiminuer T, Wu Q, Chen X, Chen H.   +9 more
europepmc   +1 more source

[Clipping: Impeachment Grounds]

Newspaper clipping discussing the grounds for presidential ...

core  

Personal Papers (MS 80-0002)

, 1962
Clipping describing a picture of Richard Wagner presenting I. H. Kempner with a silver bowl commemorating the role Mr.

core  

A Foundation Model Based CT Biomarker for Non‐Invasive Prediction of Response to Neoadjuvant Immunochemotherapy in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu, Shuchang Zhou, Qin Peng, Xiao Bao, Xiaodan Ye, Ahmet Görkem Er, Tong Tong, Mirabela Rusu, Yajia Gu, Mailin Chen, Jing Gong   +10 more
wiley   +1 more source

Pial arteriovenous fistula following aneurysm clipping: a case report of a rare complication. [PDF]

Acta Neurochir (Wien)
Li N, Feng Y, Zhang T, Zhao W.
europepmc   +1 more source