Results 171 to 180 of about 111,657 (262)
Targeted In-Defect Clipping After Colonic Endoscopic Resection: A Prospective Feasibility Study. [PDF]
Tribonias G +6 more
europepmc +1 more source
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu +8 more
wiley +1 more source
Comparing different techniques of uterine artery occlusion during laparoscopic myomectomy: a randomized controlled trial. [PDF]
Shoukry A +3 more
europepmc +1 more source
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang +10 more
wiley +1 more source
Machine Learning-Based Prediction Model of Pilgrims' Tiredness During Hajj Using Smartwatch Physiological and Mobility Indicators. [PDF]
Alshamrani M +7 more
europepmc +1 more source
Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou +14 more
wiley +1 more source
Ubiquitin beyond proteins: NoPro-clipping reveals glycogen and metabolite ubiquitination. [PDF]
Zhu K, Ahel I.
europepmc +1 more source
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen +12 more
wiley +1 more source

