Results 51 to 60 of about 3,098 (225)

A novel compound heterozygous variant in CYP19A1 resulting in aromatase deficiency with normal ovarian tissue

The Turkish Journal of Pediatrics, 2020
Background. Aromatase deficiency leading to virilization in mother and female fetuses during pregnancy is a rare disease. It is characterized by impaired estrogen production, increased gonadotropins, and ovarian cysts. Case.
Sezer Acar, Ece Böber, Mustafa Olguner, Erdener Özer, Ayhan Abacı, Bayram Özhan, Semra Gürsoy, Tufan Çankaya, Hüseyin Onay, Ahu Paketçi, İbrahim Mert Erbaş, Korcan Demir   +11 more
doaj   +1 more source

Polycystic Ovary Syndrome (PCOS) Presenting with Delayed Menarche and Clitoromegaly

Obstetrics and Gynaecology Cases - Reviews, 2022
Polycystic ovary syndrome can present with various features including delayed menarche, amenorrhoea, and enlarged clitoris, as was the case with the patient presented here.

semanticscholar   +1 more source

‘Monsters are they in Nature’: Female Masturbation and Constructions of Femininity in the Early Eighteenth Century England

Gender &History, Volume 35, Issue 2, Page 452-471, July 2023., 2023
Abstract Serious alarm about female masturbation first emerged during a transitional period for beliefs on female sexuality. This article examines the gender history of masturbation through the shifting constructions of femininity at work in early anti‐masturbation discourse.
Elizabeth Schlappa
wiley   +1 more source

Functional characterisation of novel NR5A1 variants reveals multiple complex roles in Disorders of Sex Development [PDF]

, 2017
Variants in the NR5A1 gene encoding SF1 have been described in a diverse spectrum of disorders of sex development (DSD). Recently, we reported the use of a targeted gene panel for DSD where we identified 15 individuals with a variant in NR5A1, nine of ...
Ayers, K.L. (Katie L.), Baxendale, A. (Anne), Den Bergen, J.A. (Jocelyn A.), Eggers, S. (Stefanie), Faradz, S.M.H. (Sultana), Hanna, C. (Chloe), Hersmus, R. (Remko), Lafferty, A.R. (Antony R.), Listyasari, N.A. (Nurin A.), Looijenga, L.H.J. (Leendert), Marzuki, N.S. (Nanis S.), Ohnesorg, T. (Thomas), Riedl, S. (Stefan), Robevska, G. (Gorjana), Santosa, A., Sinclair, A. (Andrew), Thompson, E.M. (Elizabeth M.), Verge, C.F. (Charles F.), Warne, G. (Garry)   +18 more
core   +6 more sources

Clitoral Epidermoid Cyst Presenting as Pseudoclitoromegaly of Pregnancy

American Journal of Perinatology Reports, 2013
Objective Acquired clitoromegaly is rare and may result from hormonal and nonhormonal causes, and evaluation of the pregnant patient with clitoromegaly invokes a specific set of differential diagnoses.
Jing W. Hughes, Marsha K. Guess, Adam Hittelman, Sallis Yip, John Astle, Lubna Pal, Silvio E. Inzucchi, Antonette T. Dulay   +7 more
doaj   +1 more source

NERVE SPARING VENTRAL CLITOROPLASTY : A NEW TREATMENT FOR CLITOROMEGALY [PDF]

Journal of Evolution of Medical and Dental Sciences, 2015
Immadi Chandra Sekhar, G. Vanaja
openalex   +2 more sources

5‐Alpha reductase deficiency; an important cause of 46, XY DSD: Report of three cases within a family

Clinical Case Reports, Volume 11, Issue 5, May 2023., 2023
Key clinical message 5‐Alpha reductase deficiency is an important cause of 46, XY disorder of sex development. Timely diagnosis and proper management by a multidisciplinary team can lead to a favorable outcome. Sex assignment should be deferred until puberty because spontaneous virilization occurs and the patient can engage in the decision‐making ...
Samaneh Noroozi Asl, Reza Ibrahimi, Sepideh Bagheri, Mojtaba Lotfi   +3 more
wiley   +1 more source

Approach to the virilizing girl at puberty [PDF]

, 2021
Virilization is the medical term for describing a female who develops characteristics associated with male hormones (androgens) at any age, or when a newborn girl shows signs of prenatal male hormone exposure at birth.
Aliu, Nijas, Cools, Martine, Flück, Christa E, Graf, Stefanie, Santi, Maristella, Trippel, Mafalda, Van de Vijver, Koen, Zeino, Mazen   +7 more
core   +2 more sources

How often are clinicians performing genital exams in children with disorders of sex development? [PDF]

, 2017
Background: We sought to determine the frequency with which genital exams (GEs) are performed in children with disorders of sex development (DSD) and ambiguous genitalia (AG) during routine visits to the pediatric endocrine clinic.
Eugster, Erica A., Tica, Stefani S.
core   +1 more source

Clitoromegaly in Childhood and Adolescence: Behind One Clinical Sign, a Clinical Sea

Sexual Development, 2018
Maria Laura Iezzi, Stefania Lasorella, Gaia Varriale, Luca Zagaroli, M Ambrosi, Alberto Verrotti   +5 more
openalex   +2 more sources