Results 91 to 100 of about 252,165 (283)
Muscle Strength and Power Changes With Gender‐Affirming Hormone Therapy
ABSTRACT Background Androgen receptors are highly expressed in upper body muscles, but changes in maximal muscle strength and power in major upper body muscles have not been investigated during gender‐affirming hormone therapy (GAHT). Objective To assess prospective changes in maximal muscle strength and muscle power from before and after 1 year of ...
Mathilde Kamp Nørlund +12 more
wiley +1 more source
PB2673: EXPERIENCES AND VIEWS OF LEUKEMIA CARERS: A GLOBAL SURVEY
Samantha Nier +11 more
doaj +1 more source
Treatment with monoclonal antibodies has revolutionized clinical medicine, especially in the fields of cancer and immunology. One of the oldest antibodies, which is widely used for the treatment of lymphomas and autoimmune diseases, is the anti-CD20 ...
Shlomo Elias +4 more
doaj +1 more source
PNP inhibitors selectively kill cancer cells lacking SAMHD1
Purine nucleoside phosphorylase inhibitors (PNP-Is) were developed to ablate transformed lymphocytes. However, only some patients with leukemia benefit from PNP-Is. We provide a molecular explanation: the deoxyribonucleoside triphosphate (dNTP) hydrolase
Tamara Davenne, Jan Rehwinkel
doaj +1 more source
Evidence for somatic selection of natural autoantibodies. [PDF]
Natural autoantibodies are primarily immunoglobulin M (IgM) antibodies that bind to a variety of self-antigens, including self-IgG. Accounting for a large proportion of the early B cell repertoire, such polyspecific autoantibodies are speculated to ...
Carson, DA +3 more
core
High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target [PDF]
Laura Llaó Cid +28 more
openalex +1 more source
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies. [PDF]
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Martino EA +10 more
europepmc +2 more sources
18F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients [PDF]
Sylvain Chantepie +14 more
openalex +1 more source

