Results 151 to 160 of about 1,324,164 (376)

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Methods Matter: Beating the Backward Clock [PDF]

open access: yes, 2017
In “Beat the (Backward) Clock,” we argued that John Williams and Neil Sinhababu’s Backward Clock Case fails to be a counterexample to Robert Nozick’s or Fred Dretske’s Theories of Knowledge.
Adams, Fred   +2 more
core  

Acceleration and Clocks [PDF]

open access: yesScience, 1976
W. T. Vetterling, R. V. Pound
openaire   +3 more sources

A Clock of Precision [PDF]

open access: yesProceedings of the Physical Society of London, 1916
The principal feature of the author's arrangement is the employment of a "slave" clock to do the great part of the work, leaving the master pendulum no function beyond that of controlling the rate of the other. The master pendulum swings freely except for a short period (about one-fifth of a second) every minute, during which it receives an impulse ...
openaire   +3 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Synchronous ten-megabit biphase detector [PDF]

open access: yes, 1973
Synchronous phase-lock-loop detector accepts distorted input and generates jitter-free clock. Data-detection circuitry takes advantage of this clock and employs integrate-and-dump decision circuit to provide near-theoretically ideal data ...
Balliet, L.
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

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