Results 151 to 160 of about 1,354,268 (327)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Critical review of aging clocks and factors that may influence the pace of aging

Frontiers in Aging
Background and objectivesAging clocks are computational models designed to measure biological age and aging rate based on age-related markers including epigenetic, proteomic, and immunomic changes, gut and skin microbiota, among others. In this narrative
Mildred Min, Mildred Min, Mildred Min, Caitlin Egli, Caitlin Egli, Caitlin Egli, Ajay S. Dulai, Ajay S. Dulai, Raja K. Sivamani, Raja K. Sivamani, Raja K. Sivamani, Raja K. Sivamani, Raja K. Sivamani   +12 more
doaj   +1 more source

FLOWERING LOCUS C-dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]

, 2006
Neeraj Salathia, Seth J Davis, James R. Lynn, Scott D. Michaels, Richard M. Amasino, Andrew J. Millar   +5 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Circadian Clocks and Metabolism

, 2013
Biliana Marcheva, Kathryn Moynihan Ramsey, Clara Bien Peek, Alison H. Affinati, Eléonore Maury, Joseph Bass   +5 more
openalex   +2 more sources

Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat [PDF]

, 2018
Panteleimon D. Mavroudis, Debra C. DuBois, Richard R. Almon, William J. Jusko   +3 more
openalex   +1 more source

Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism

, 2022
Mathias Vanmunster, Ana Victoria Rojo‐García, Alexander Pacolet, Sebastiaan Dalle, Katrien Koppo, Ilse Jonkers, Rik Lories, Frank Suhr   +7 more
openalex   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Multicellularity enriches the entrainment of Arabidopsis circadian clock [PDF]

, 2017
Kosaku Masuda, Ryota Kitaoka, Kazuya Ukai, Isao T. Tokuda, Hirokazu Fukuda   +4 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source