Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids. [PDF]
Meijer HA+16 more
europepmc +1 more source
Clockmaking, Past and Present With which is incorporated the more important portions of “Clocks, Watches and Bells,” by the late Lord Grimthorpe, relating to Turret Clocks and Gravity Escapements [PDF]
George Gordon
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Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva+5 more
wiley +1 more source
Insect circadian plasticity as a proposed target for the expression of parasite extended phenotypes. [PDF]
Dopp J, de Bekker C.
europepmc +1 more source
Original Documents Agreement Between the Dean and Chapter of St. Paul’s, London, and Walter the Orgoner, of Southwark, Relating to a Clock in St. Paul’s Church Dated November 22, 1344 [PDF]
Frederic Madden
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Addition to a Paper "On the Mathematical Theory and Practical Defects of Clock Escapements, &c." By James Mackenzie Bloxam, Esq., being a series of posthumous notes [PDF]
George Biddell Airy
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