Results 121 to 130 of about 139,098 (277)

Langevin equation approach to granular flows in narrow pipes

open access: yes, 1998
The flow of granular material through a rough narrow pipe is described by the Langevin equation formalism. The stochastic force is caused by irregular interaction between the wall and the granular particles.
Dirk Rosenkranz   +4 more
core   +1 more source

Development of a computer programme for the design of municipal wastewater treatment facilities - Part 1 : the incoming conduit and screening faculty [PDF]

open access: yes, 1994
A computer programme was developed using Fortran utilizing IBM-PC compatible microcomputers to design the primary sedimentation or clarification in a municipal wastewater treatment plant.
Demun, Amat Sairin
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Multidimensional Characterization of Formation Damage Mechanisms in Ancient Carbonate Reservoirs: Synergistic Effects of Inorganic‐Organic Interactions

open access: yesEnergy Science & Engineering
Formation clogging in carbonate gas reservoirs is a significant challenge in natural gas extraction, particularly due to the complex mineral composition and physicochemical characteristics of carbonate rocks, which make clogging phenomena even more ...
Jin Pang   +5 more
doaj   +1 more source

A feasible method for the composition analysis and chemical remediation of clogging matter in subsurface flow constructed wetlands

open access: yesWater Cycle
The problem of clogging, especially biological clogging, makes the long-term operation of subsurface flow constructed wetlands challenging. This study focused on the two subsurface flow constructed wetlands receiving reclaimed water near the Tuhai River ...
Yu Zheng   +9 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

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