Results 121 to 130 of about 4,828 (201)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Autofecundación e hibridación en un clon sexual del zacate apomictico cenchrus ciliaris l.
, 1994 "Con los objetivos de producir y evaluar plantas S1 y F1 de zacate buffel y seleccionar genotipos superiores de reproducción apomíctica, se realizaron autofecundaciones y cruzamientos en el clon sexual TAM-CRD B1-s de zacate buffel en invernadero.
Gómez Martínez, Susana
core
Digital metamorphosis: A fenomeno called Clon [PDF]
, 2007 Tema del mesClon. Cyberzine de Arte y Cultura es un proyecto de la Universidad Autónoma Metropolitana de Xochimilco, que nace en 1997 con el fin de investigar el uso que se le puede dar a las Tecnologías de Información y Comunicación (TIC) en la creación
ANTONIO DEL RIVERO HERRERA +1 more
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Propagación de clon plus a de Sequoia sempervirens (D.Don). Endl. Mediante cultivo in vitro
, 2007 72 páginasSe evaluó el efecto de dos tipos de explantes (apical y basal) y tres concentraciones de citoquinina (0; 0,5; y 1,0 mg/l BAP), en multiplicación in vitro de segmentos de brotes del clon "Plus A" de S.
Suazo Herrera, Daniela Eugenia
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Cultivos Tropicales, 2012 Se presentan las principales características del clon 'Criollo-9', saneado y rejuvenecido mediante la técnica de cultivo de meristemos. Este genotipo se mostró resistente ante las plagas y enfermedades que afectan a este cultivo y tuvo un elevado ...
Humberto Izquierdo Oviedo +1 more
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