Results 131 to 140 of about 7,984 (276)

'CRIOLLO-9', UN CULTIVAR DE AJO RESISTENTE A LAS ENFERMEDADES FITOPATÓGENAS Y ELEVADO POTENCIAL DE RENDIMIENTO

open access: yesCultivos Tropicales, 2012
Se presentan las principales características del clon 'Criollo-9', saneado y rejuvenecido mediante la técnica de cultivo de meristemos. Este genotipo se mostró resistente ante las plagas y enfermedades que afectan a este cultivo y tuvo un elevado ...
Humberto Izquierdo Oviedo   +1 more
doaj  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Performance Comparison of Different Approaches in Genotyping MHC-DRB: The Contrast between Single-Locus and Multi-Locus Species. [PDF]

open access: yesAnimals (Basel), 2022
Svetličić I   +8 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Evaluación de clones promisorios y variedades de papa de uso local en el estado Mérida,Venezuela

open access: yesAIA Avances en Investigación Agropecuaria, 2018
Con el objetivo de seleccionar los materiales de papa con mejor adaptación a las diferentes localidades consideradas se evaluaron clones promisorios (382151.22, 382121.25, 386528.7), variedades comerciales (Dorinia, Marilinia, Muskainia, Cristalinia) y ...
Lourdes González   +2 more
doaj  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Eficiencias en el uso de nitrógeno, fósforo y potasio en clones de cacao (Theobroma cacao L.)

open access: yesBioagro, 2014
El manejo de la fertilización es un aspecto relevante para el desarrollo de los cultivos ya que un excesivo aporte de nutrientes, puede sobrepasar la capacidad de absorción de la planta y generar un riesgo ambiental, como también, pérdida económica para ...
Yina Puentes-Páramo   +2 more
doaj  

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