ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl +6 more
wiley +1 more source
Effects of Different Management Practices on Ramet System Dynamics in Moso Bamboo (<i>Phyllostachys edulis</i>) Forests, China. [PDF]
Gao G +7 more
europepmc +1 more source
Deciphering the biosynthetic pathways of lichen acids
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim +11 more
wiley +1 more source
Establishment of an efficient tissue culture system for Paeonia ostii by combining vernalization and etiolation pretreatment with optimized culture conditions. [PDF]
Li M +6 more
europepmc +1 more source
PEP725: 15 years of driving European and global phenology science
Summary Phenology – the timing of seasonal biological events – is a sensitive indicator of climate change and ecosystem dynamics. Long‐term, broad‐scale phenological data are crucial for understanding and predicting plant responses to environmental change.
Barbara Templ +4 more
wiley +1 more source
Evaluating the impact of a 10 year reduction in critically important antibiotic use on the occurrence of antibiotic resistance in <i>E. coli</i> from cattle, dogs and cats in France. [PDF]
Collineau L +8 more
europepmc +1 more source
Reconciling links between diversity and population stability across global plant communities
Summary Maintaining ecological stability is essential for sustaining ecosystem functions and the benefits they provide to society. Ecological theory predicts that plant diversity destabilizes local populations, yet empirical studies report variable effects.
Xiaobin Pan +51 more
wiley +1 more source
A case study of critical points for the entry and spread of Salmonella Infantis in a broiler farm. [PDF]
Papić B +5 more
europepmc +1 more source
Epigenetic regulation of mycorrhizal symbioses: from plastic responses to transgenerational legacies
Summary Mycorrhizal symbioses represent one of the most widespread and ecologically significant plant–microbe interactions, shaping plant nutrition, stress resilience, and ecosystem functioning. Beyond their role in nutrient exchange and systemic defense, growing evidence suggests that these symbioses also influence plant plasticity within and across ...
Gerson Beltrán‐Torres +9 more
wiley +1 more source
Exploring the role of BpPIN3 in hormonal regulation and branching morphogenesis of Betula pendula. [PDF]
Chen K +7 more
europepmc +1 more source

