Results 121 to 130 of about 2,714,710 (286)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Success of the clonal plant Carex arenaria under contrasting light regimes

open access: yes, 1999
Röttgermann M, Steinlein T, Beyschlag W. Success of the clonal plant Carex arenaria under contrasting light regimes. Verhandlungen der Gesellschaft für Ökologie.
Beyschlag, Wolfram   +2 more
core  

Synthetic clonal reproduction through seeds

open access: yes, 2011
oai:HAL:hal-00999890v1Cloning through seeds has potential revolutionary applications in agriculture, because it would allow vigorous hybrids to be propagated indefinitely.
Chan, Simon, S.   +32 more
core   +1 more source

Formation of single-dominant-species patches of Dicranopteris dichotoma primarily influenced by understory light intensity

open access: yesFrontiers in Plant Science
IntroductionThe Dicranopteris dichotoma fern community plays vital roles in nutrient sequestration, succession regulation, and ecological threshold control. However, the mechanisms underlying the formation of the D.
Dubin Dong   +6 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

The effect of the duration of hypoxia on phenolic accumulation in roots of clonal Eucalyptus marginata and their subsequent infection with Phytophthora cinnamomi [PDF]

open access: yes, 1997
Roots of E. marginata exposed to hypoxia show increased resistance to infection by P. cinnamomi. A more rapid production of phenolics has previously been shown to be related to increased resistance in clonal E. marginata.
Hardy, G.E.St.J.   +4 more
core  

Caloric restriction extends lifespan in a clonal plant

open access: yesEcology Letters
Abstract When subjected to dietary caloric restriction (CR), individual animals often outlive well‐fed conspecifics. Here, we address whether CR also extends lifespan in plants. Whereas caloric intake in animals comes from ingestion, in plants it derives from photosynthesis.
Suzanne L. Chmilar   +5 more
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy