Results 131 to 140 of about 2,714,710 (286)

Patterns of Genetic and Clonal Diversity in Myriophyllum spicatum in Streams and Reservoirs of Republic of Korea

Myriophyllum spicatum is a globally distributed aquatic plant capable of sexual and clonal reproduction. Despite its ecological importance and biochemical potential, studies on its genetic and clonal structure in freshwater systems throughout South Korea
Kang-Rae Kim, Jaeduk Goh, Mi-Hwa Lee, Jeong-Nam Yu, Eun-Hye Kim   +4 more
core   +1 more source

Effects of lead contamination on the clonal propagative ability of Phragmites australis (common reed) grown in wet and dry environments

, 2015
Clonal propagation is important for the survival and maintenance of the common reed Phragmites australis. Pot culture experiments were conducted to investigate the effects of lead (Pb) concentration (0, 500, 1500, 3000, 4500mg -1)) and water stress on ...
X. Y. Li, J. X. Lin, L. Y. Cheng, J. F. Wang, N. Zhang, Y. H. Yang, C. S. Mu, Z. L. Li, A. X. Wang, J. W. Zhang   +9 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Is Clonal Integration a Buffer for the Stress of Resource Acquisition Depletion in Eichhornia crassipes (Pontederiaceae) Ramets?

Stresses
Natural selection favors the allocation of finite resources to different functions maximizing fitness. In this sense, some functions may decrease whereas others increase when resources are limited in a process called a trade-off. However, a great variety
Guilherme Ramos Demetrio, Dalton Serafim, Flávia de Freitas Coelho   +2 more
doaj   +1 more source

DNA Methylation Can Mediate Local Adaptation and Response to Climate Change in the Clonal Plant Fragaria vesca: Evidence From a European-Scale Reciprocal Transplant Experiment. [PDF]

Front Plant Sci, 2022
Sammarco I, Münzbergová Z, Latzel V.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Role of clonal integration in plant competition

Clonal growth enables plant to replicate rooting units (i.e. ramets), adding another hierarchical level to plant modularity. Clonal growth is very common, at least in the temperate flora, and widespread over the angiosperm phylogenetic tree.
Duchoslavová, Jana
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Cultivation of myrobalan plum on clonal rootstocks

, 2001
A brief review of the literature on the problem “Clonal rootstocks for the stone-fruit crops” has made. The advantages of planting stock growing for myrobalan plum on the clonal rootstocks are displayed and demands to these rootstocks are presented. Weak
S.A. Vasuta, Vasuta, S.A.
core   +1 more source