Results 221 to 230 of about 88,997 (296)

Phytochemical Composition of Clonally Propagated <i>Artemisia annua</i> L. in Different Geographical Locations and Its Commercial Supplement Quality. [PDF]

Molecules
Towler MJ, Kellogg JJ, Weathers PJ.
europepmc   +1 more source

Data‐Driven Bulldozer Blade Control for Autonomous Terrain Leveling

Advanced Robotics Research, EarlyView.
A simulation‐driven framework for autonomous bulldozer leveling is presented, combining high‐fidelity terramechanics simulation with a neural‐network‐based reduced‐order model. Gradient‐based optimization enables efficient, low‐level blade control that balances leveling quality and operation time.
Harry Zhang, Ganesh Arivoli, Huzaifa Unjhawala, Luning Bakke, Radu Serban, Dan Negrut   +5 more
wiley   +1 more source

Investigation of VIM-1-producing <i>Enterobacter</i> spp. across Switzerland: clonal dissemination and plasmid transmission. [PDF]

Antimicrob Agents Chemother
Seth-Smith HMB, Greutmann M, Findlay J, Beckmann C, Berlinger L, Brugger SD, Capaul R, Greub G, Gruner E, Keller PM, Nolte O, Roloff T, Tschudin-Sutter S, Zingg W, Nordmann P, Poirel L, Egli A, NARA Network.   +17 more
europepmc   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Repeated Independent Formation of Triploid Lineages Contributes to Clonal Diversity in Heteronotia binoei Parthenogens. [PDF]

Mol Ecol
O'Hara KE, Zozaya SM, Hahn EE, Holleley CE, Moritz C.   +4 more
europepmc   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

A fundamental relationship between TCR diversity, repertoire size and systemic clonal expansion: insights from 30,000 TCR<i>β</i> repertoires. [PDF]

Front Immunol
Zahid HJ, May D, Robins H, Greissl J.
europepmc   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Decoding clone evolution in HER2 amplified breast cancer through single-cell and spatial transcriptomics analysis of copy number variations. [PDF]

Sci Rep
Yang J, Li Y, Luo S, Wang J, Duan Y.
europepmc   +1 more source