Results 241 to 250 of about 39,199 (304)

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

FT-IR Spectroscopy to Discriminate Old from New <i>Pseudomonas aeruginosa</i> Infections in People with Cystic Fibrosis. [PDF]

Int J Mol Sci
Rossitto M, Raimondi S, Fox V, Tuccio Guarna Assanti V, Essa N, Lepanto MS, Cristiano M, Cortazzo V, Agosta M, Majo F, Cutrera R, Perno CF, Bernaschi P, Vrenna G.   +13 more
europepmc   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Refractory Celiac Disease: Nutritional Failure, Immune Dysregulation, and Lymphomagenesis. [PDF]

Nutrients
Aggeletopoulou I, Pastras P, Kalafateli M, Triantos C.   +3 more
europepmc   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source

Confined B-Cell Reconstruction and High T-Cell Clonality Define Clinical Response to Cladribine Treatment. [PDF]

Ann Neurol
Schneider-Hohendorf T, Eveslage M, Wirth T, Wünsch C, Schumann EM, Lünemann JD, Wiendl H, Klotz L, Schwab N.   +8 more
europepmc   +1 more source

Dynamics of Spinal Fluid Immune Cell Alterations Following Cladribine Tablet Treatment in Multiple Sclerosis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Smirnov RA, Cantoni C, Lee K, Agnihotri RA, Axtell RC, Salter A, Lancia S, Paley MA, Hayward B, Korich J, Evans E, Pardo G, Obeidat AZ, Stuve O, Bar-Or A, Artyomov MN, Cross AH, Edelson BT, Wu GF.   +18 more
europepmc   +1 more source

TRBC1/TRBC2 Immunophenotyping Provides Added Value During the Diagnostic Workup of T-Cell Lymphoma. [PDF]

EJHaem
Taylor J, Lakum T, Bevan S, Freeman T, Boot J, Bigogno CM, Raine J, Hookway E, Medani H, Calaminici M, Okosun J, Grantham M, Araf S, Smith M, Butler T, Farren T.   +15 more
europepmc   +1 more source