Results 211 to 220 of about 790,447 (335)

Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer. [PDF]

Cell Rep Med
Newsome RC, Liu H, Agbodzi B, Gharaibeh RZ, Zhou L, Jobin C.   +5 more
europepmc   +1 more source

Clonal variation in albumin messenger RNA activity in hepatoma cells.

, 1976
Jerry A. Peterson
openalex   +2 more sources

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells [PDF]

, 2000
Qinghua Zhang, Min Ye, Xinyan Wu, Shuangxi Ren, Zhao Meng, Chunjun Zhao, Gang Fu, Yu Shen, Huiyong Fan, Gang Lü, Ming Zhong, X.Z. Shawn Xu, Ze‐Guang Han, Jiwang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Gengxi Hu, Jian Ren Gu, Sai‐Juan Chen, Zhu Chen   +20 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Whole Genome and Single-Cell RNA Sequencing Reveals Clonal Evolution and Heterogeneity of Secondary Plasma Cell Leukemia: A Case Report. [PDF]

EJHaem
Suzuki T, Yokomori R, Sanda T, Ri M, Iida S.   +4 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

IL2/IL15 Signaling Induces NK Cell Production of FLT3LG, Augmenting Anti-PD-1 Immunotherapy. [PDF]

Cancer Immunol Res
Avanessian SC, van den Bijgaart RJE, Chew NW, Supper VM, Tang TT, Zhang Y, Zhao YQ, Abe K, Gauthier J, Barry KC.   +9 more
europepmc   +1 more source

Stem Cells, Cloning, and Regulation [PDF]

Mayo Clinic Proceedings, 2005
openaire   +2 more sources

Patients Do Not Need Congressman Langevin’s Clone-to-Kill Bill [PDF]

, 2010
Austriaco, Nicanor
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source