Results 311 to 320 of about 790,447 (335)
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Single cell sorting and cloning
Journal of Immunological Methods, 2000Cell sorters now allow the selection of cells and other bodies according to a range of quite diverse criteria. The additional refinement that allows the sorting of individual cells based on these criteria has seen application in many fields of research.
F L, Battye, A, Light, D M, Tarlinton
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Blood, 2006
AbstractThe detection of a monoclonal immunoglobulin in serum or urine usually raises concerns about the size of the underlying B-cell-derived clone and possible systemic effects caused by its expansion. However, a small clone can synthesize a very toxic protein, producing devastating systemic damage and protean clinical presentations.
MERLINI, GIAMPAOLO, STONE MJ
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AbstractThe detection of a monoclonal immunoglobulin in serum or urine usually raises concerns about the size of the underlying B-cell-derived clone and possible systemic effects caused by its expansion. However, a small clone can synthesize a very toxic protein, producing devastating systemic damage and protean clinical presentations.
MERLINI, GIAMPAOLO, STONE MJ
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Modular cloning in plant cells
Trends in Plant Science, 2005New plant genes are being discovered at a rapid pace. Yet, in most cases, their precise function remains elusive. The recent advent of recombinational cloning techniques has significantly improved our ability to investigate gene functions systematically.
Karimi, Mansour +2 more
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1998
The word “clone” is used to describe a cell population that has derived from a single cell. Such single cells are termed “clonogenic” and only a small proportion of normal cells and probably a higher proportion of tumor cells have the proliferative capabilities required to give rise to clones.
Shirley McBride +2 more
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The word “clone” is used to describe a cell population that has derived from a single cell. Such single cells are termed “clonogenic” and only a small proportion of normal cells and probably a higher proportion of tumor cells have the proliferative capabilities required to give rise to clones.
Shirley McBride +2 more
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1984
T cell clones are useful models for studying lymphocyte function both at the level of the individual cell and in interacting systems. Murine cytolytic and non- cytolyic T cell clones have been obtained with relative ease, and the particular procedure used to derive and maintain T cell clones may influence profoundly the characteristics of the resulting
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T cell clones are useful models for studying lymphocyte function both at the level of the individual cell and in interacting systems. Murine cytolytic and non- cytolyic T cell clones have been obtained with relative ease, and the particular procedure used to derive and maintain T cell clones may influence profoundly the characteristics of the resulting
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Cloning of fresh lymphoma cells
Medical and Pediatric Oncology, 1981AbstractWe attempted to induce in vivo clonal growth of neoplastic lymphoid cells from fresh specimens of involved tissue from 22 patients with non‐Hodgkin lymphoma (NHL). Conditioned media derived from two human B‐lymphocyte tissue culture lines were tested for their ability to promote colony growth.
M, Nishikori +3 more
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Myoglobin-Reactive T Cell Clones
1982Myoglobin has been used for a considerable period of time as a “model” antigen for immunological studies. Since the sequence and crystal structure of myoglobin from sperm whale skeletal muscle are well known, myoglobin can be studied in great detail as an antigen.
A J, Infante, M Z, Atassi, C G, Fathman
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2003
Techniques for generating human T-cell clones (TCCs) were first described nearly two decades ago (1, 2). This was a direct consequence of the discovery of T-cell growth factor and the subsequent ability to propagate T-cells over extended periods (3).
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Techniques for generating human T-cell clones (TCCs) were first described nearly two decades ago (1, 2). This was a direct consequence of the discovery of T-cell growth factor and the subsequent ability to propagate T-cells over extended periods (3).
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Cell Biology International Reports, 1978
Abstract The major problem in studying gene expression in eukaryotic organisms is the complexity of the eukaryotic genome. We would like to have the same detailed understanding of the genetics of eukaryotes as has been obtained for λ bacteriophage but are faced with the daunting statistic that the human genome could accommodate nearly 100,000 times ...
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Abstract The major problem in studying gene expression in eukaryotic organisms is the complexity of the eukaryotic genome. We would like to have the same detailed understanding of the genetics of eukaryotes as has been obtained for λ bacteriophage but are faced with the daunting statistic that the human genome could accommodate nearly 100,000 times ...
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1984
Publisher Summary This chapter discusses the uses of cloned normal T lymphocytes. T-cell clones offer unique advantages for a variety of immunological studies. The availability of large numbers of defined, homogeneous cell T cells will greatly facilitate efforts to identify the T-cell receptor for antigen and to define unambiguously the molecular ...
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Publisher Summary This chapter discusses the uses of cloned normal T lymphocytes. T-cell clones offer unique advantages for a variety of immunological studies. The availability of large numbers of defined, homogeneous cell T cells will greatly facilitate efforts to identify the T-cell receptor for antigen and to define unambiguously the molecular ...
openaire +1 more source