Results 101 to 110 of about 3,181,244 (296)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Feature extraction of overlapping hevea leaves: A comparative study
Information Processing in Agriculture, 2018 Automation of rubber tree clone classification has inspired research into new methods of leaf feature extraction. In current practice, rubber clone inspectors has been using several leaf features to identify clone types.
Sule T. Anjomshoae +1 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Detecting Code Clones: A review
CoRR, 2016 Code clone detection is involved with detecting duplicated fragments of code within a code base. Detecting these clones is useful for maintenance operations which require editing the clones. The tools developed are expected to be robust enough to identify clones even when they have been modified, whilst preserving reasonable recall and precision rates.
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A structural damage detection and classification algorithm based on clone selection
, 2013 Inspired by identification ability of biological immune system, damage detection and classification problem in structural health monitoring is studied based on the autonomous, adaptive and evolutional artificial immune theory and method.
Zhou Y(周悦) +3 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Big Data and Cognitive ComputingAs Large Language Models (LLMs) continue to advance, their capabilities in code clone detection have garnered significant attention. While much research has assessed LLM performance on human-generated code, the proliferation of LLM-generated code raises ...
Zixian Zhang, Takfarinas Saber
doaj +1 more source
Fast Code Clone Detection Based on Weighted Recursive Autoencoders
IEEE Access, 2019 Code cloning considerably facilitates software development but also leads to recurring bugs and other software quality problems. In this paper, we propose a fast code clone detection method based on weighted recursive autoencoders (RAE) to measure code ...
Jie Zeng +3 more
doaj +1 more source