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Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial.

open access: yesJAMA
Walsh TS   +32 more
europepmc   +1 more source
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Clonidine

Advances in Alcohol & Substance Abuse, 1988
Clonidine has provided a nonaddicting solution to an ancient problem, opiate withdrawal without opiates. Gold and colleagues' initial demonstration that this alpha 2 adrenergic agonist could be used to detoxify opiate addicts provided the first nonaddicting treatment for opiate dependency.
H, Roehrich, M S, Gold
openaire   +3 more sources

Clonidine Poisoning

Pediatrics, 1976
Clonidine (Catapres, Boehringer Ingelheim) is a relatively new hypotensive agent with complex pharmacologic actions on the autonomic nervous system. Little is known about its effects and side effects in children. An interesting combination of these were seen in a child who accidentally ingested an unknown quantity of this drug.
G S, Pai, D J, Lipsitz
openaire   +2 more sources

Clonidine Overdose

Critical Care Medicine, 1983
A case of acute intoxication in a 60-yr-old woman who ingested 20 mg of clonidine is presented. The patient showed CNS depression (bradycardia, hypotonia) with systemic hypertension and peripheral vasoconstriction. She was treated with atropine and sodium nitroprusside. There was no recurrence and the patient recovered in 8 days.
L, Marruecos   +3 more
openaire   +2 more sources

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