Results 271 to 280 of about 80,817 (324)
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Pediatrics, 1976
Clonidine (Catapres, Boehringer Ingelheim) is a relatively new hypotensive agent with complex pharmacologic actions on the autonomic nervous system. Little is known about its effects and side effects in children. An interesting combination of these were seen in a child who accidentally ingested an unknown quantity of this drug.
G S, Pai, D J, Lipsitz
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Clonidine (Catapres, Boehringer Ingelheim) is a relatively new hypotensive agent with complex pharmacologic actions on the autonomic nervous system. Little is known about its effects and side effects in children. An interesting combination of these were seen in a child who accidentally ingested an unknown quantity of this drug.
G S, Pai, D J, Lipsitz
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Critical Care Medicine, 1983
A case of acute intoxication in a 60-yr-old woman who ingested 20 mg of clonidine is presented. The patient showed CNS depression (bradycardia, hypotonia) with systemic hypertension and peripheral vasoconstriction. She was treated with atropine and sodium nitroprusside. There was no recurrence and the patient recovered in 8 days.
L, Marruecos +3 more
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A case of acute intoxication in a 60-yr-old woman who ingested 20 mg of clonidine is presented. The patient showed CNS depression (bradycardia, hypotonia) with systemic hypertension and peripheral vasoconstriction. She was treated with atropine and sodium nitroprusside. There was no recurrence and the patient recovered in 8 days.
L, Marruecos +3 more
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Journal of Cardiovascular Pharmacology, 1980
The effects of clonidine on renal hemodynamics and renal function make it a particularly useful antihypertensive agent. During treatment of hypertensive patients with clonidine, renal blood flow and glomerular filtration rate are well maintained, and renin secretion is reduced. Early in therapy, a slight tendency to retain salt and water may be seen as
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The effects of clonidine on renal hemodynamics and renal function make it a particularly useful antihypertensive agent. During treatment of hypertensive patients with clonidine, renal blood flow and glomerular filtration rate are well maintained, and renin secretion is reduced. Early in therapy, a slight tendency to retain salt and water may be seen as
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CLONIDINE IN MIGRAINE PROPHYLAXIS
Obstetrical & Gynecological Survey, 1977SYNOPSISClonidine chloride, 25 ug three times per day, decreased the mean number of headache attacks per month to 2.26 compared to 3.94 before treatment and 2.98 during placebo use in 50 migraineurs. Fifty ug clonidine t.i.d. decreased mean number of attacks from 4 before treatment to 1.88 during treatment and 2.49 during placebo.
H. Hakkarainen +3 more
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Neonatal Network, 2000
TO PROVIDE OPTIMAL CARE FOR selected neonates in a neonatal intensive care unit (NICU), opioid sedation and analgesia may be required. Not only is this a caring approach, but there is mounting evidence that biochemical and physiologic stress responses to acute disease may directly influence the neonate’s outcome.1Opioid analgesia and sedation decrease ...
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TO PROVIDE OPTIMAL CARE FOR selected neonates in a neonatal intensive care unit (NICU), opioid sedation and analgesia may be required. Not only is this a caring approach, but there is mounting evidence that biochemical and physiologic stress responses to acute disease may directly influence the neonate’s outcome.1Opioid analgesia and sedation decrease ...
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Agmatine: an endogenous clonidine-displacing substance in the brain.
Science, 1994Clonidine, an antihypertensive drug, binds to alpha 2-adrenergic and imidazoline receptors. The endogenous ligand for imidazoline receptors may be a clonidine-displacing substance, a small molecule isolated from bovine brain.
Gen Li +5 more
semanticscholar +1 more source
Southern Medical Journal, 1982
Clonidine hydrochloride (Catapres), a potent antihypertensive agent, has been in clinical use since 1974 in the United States. Clonidine, an alpha-adrenergic receptor agonist, stimulates central alpha receptors in the depressor site of the vasomotor center of the medulla oblongata and hypothalamus, which diminishes efferent sympathetic tone to the ...
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Clonidine hydrochloride (Catapres), a potent antihypertensive agent, has been in clinical use since 1974 in the United States. Clonidine, an alpha-adrenergic receptor agonist, stimulates central alpha receptors in the depressor site of the vasomotor center of the medulla oblongata and hypothalamus, which diminishes efferent sympathetic tone to the ...
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Antianginal Effects of Clonidine
Journal of Cardiovascular Pharmacology, 1986The effects of clonidine, a central alpha-adrenoceptor agonist, were studied in 12 patients with chronic stable effort angina pectoris in an 18-week randomized, double-blind, two-period (6 weeks each) crossover study with a 3-week inter-period washout phase.
Gary E. Sander +4 more
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Clonidine in the Treatment of Hypertension
Journal of Cardiovascular Pharmacology, 1980Clonidine has clearly been shown to be effective in the treatment of all grades of hypertension. Clonidine by itself, when compared with placebo, has proved its worth in the treatment of essential hypertension; it has also been found to be more effective than diuretic treatment alone.
Norman M Kaplan, Bruce N. Garrett
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American Journal of Health-System Pharmacy, 1979
The pharmacology and pharmacokinetics of clonidine and the symptoms and treatment of acute clinidine overdosage are reviewed. Clonidine, a relatively safe and effective antihypertensive agent when used at therapeutic dosages, reduces blood pressure through a centrally mediated reduction in vasomotor tone.
Christopher S. Conner +1 more
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The pharmacology and pharmacokinetics of clonidine and the symptoms and treatment of acute clinidine overdosage are reviewed. Clonidine, a relatively safe and effective antihypertensive agent when used at therapeutic dosages, reduces blood pressure through a centrally mediated reduction in vasomotor tone.
Christopher S. Conner +1 more
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