Results 61 to 70 of about 7,005 (218)

Flatworms have lost the right open reading frame kinase 3 gene during evolution [PDF]

, 2015
All multicellular organisms studied to date have three right open reading frame kinase genes (designated riok-1, riok-2 and riok-3). Current evidence indicates that riok-1 and riok-2 have essential roles in ribosome biosynthesis, and that the riok-3 gene
Amani, Parisa, Ansell, Brendan R. E., Boag, Peter R., Breugelmans, Bert, Gasser, Robin B., Hofmann, Andreas, Jex, Aaron R., Sternberg, Paul W., Stroehlein, Andreas J., Young, Neil D.   +9 more
core   +1 more source

Over one‐third of cancer cases and two‐fifths of cancer deaths in southern China are preventable: Insights from the latest representative population‐based cancer registry data and risk factor survey

International Journal of Cancer, Volume 158, Issue 4, Page 909-923, 15 February 2026.
What's new? This study quantified the cancer burden attributable to modifiable risk factors in Guangdong, the most populous and economically advanced province in southern China. By evaluating 15 modifiable risk factors, the study reveals that over one‐third of cancer cases and two‐fifths of cancer deaths in the region could potentially be prevented ...
Xiaolan Wen, Yu Liao, Jiayue Li, Qian Zhu, Xinmei Lin, Bingfeng Han, Li Li, Ru Chen, Ruilin Meng, Ni Xiao, Xueyan Zheng, Xiaojun Xu, Dejian Zhao, Yue Gao, Liming Pu, Ye Wang, Wenqiang Wei, Shaoming Wang   +17 more
wiley   +1 more source

Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice

Aging Cell, Volume 25, Issue 1, January 2026.
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds, Sharon E. Mitchell, Xiaojing Yang, Wei Guo, Emily Chen, Peter D. Adams, John R. Speakman   +6 more
wiley   +1 more source

Application of DNA-based diagnostics in detection of schistosomal DNA in early infection and after drug treatment [PDF]

, 2011
Background Research is now focused on identification of sensitive and specific diagnostic tests for early identification of schistosomal infection and evaluation of chemotherapy in field situations in China ...
Cen Wang, Lin Chen, Xuren Yin, Wanquan Hua, Min Hou, Minjun Ji, Chuanxin Yu, Guanling Wu   +7 more
core   +1 more source

Mechanisms of Action and Biomarker Potential of ncRNAs in Hepatocellular Carcinoma and Liver Fibrosis: A Review

Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Liver diseases constitute a major global health burden, contributing substantially to morbidity and mortality worldwide. Although effective therapeutic strategies have been developed for key risk factors, such as hepatitis C infection, therapeutic options for most other liver diseases remain limited.
Eun Jung Sohn, Sae-Ock Oh, Suraiya Saleem   +2 more
wiley   +1 more source

CsNOSIP Reverses NLRP3 Inflammasome Activation Induced by CsESPs via Inducing iNOS and NO Expression and Inhibiting NF-κB Signaling Pathway in Macrophages

Parasitologia
Excretory/secretory products from parasites (ESPs) can act as pathogen-associated molecular patterns (PAMPs) to activate innate immunity. Parasites may achieve immune evasion by modulating the interaction between PAMPs and the nucleotide-binding ...
Xuran Yang, Huimin Dong, Xiangzhan Kong, Xuerong Li, Xuejing Chi, Qiannan Liu, Xinbing Yu, Wenfang Li, Yan Huang   +8 more
doaj   +1 more source

Mitochondrial and nuclear ribosomal DNA dataset supports that Paramphistomum leydeni (Trematoda: Digenea) is a distinct rumen fluke species [PDF]

, 2015
BACKGROUND: Rumen flukes parasitize the rumen and reticulum of ruminants, causing paramphistomiasis. Over the years, there has been considerable debate as to whether Paramphistomum leydeni and Paramphistomum cervi are the same or distant species. METHODS:
Dong-Hui Zhou, Guo-Hua Liu, Jian-Zhi Liu, Jun Ma, Jun-Jun He, Xing-Quan Zhu, Yi Liu   +6 more
core   +1 more source

Fish Pathogens and Associated Zoonotic Risks in Aquaculture: A Global One Health Perspective

Aquaculture, Fish and Fisheries, Volume 5, Issue 6, December 2025.
ABSTRACT Aquaculture sector is a key contributor to global food and nutritional security, yet its rapid intensification has heightened concerns about the emergence and spread of zoonotic fish pathogens that threaten human, animal and environmental health.
Fredrick Juma Syanya, Sajna Beegum, Zachariy Oreko Winam, Fazeena Fariq, A. R. Nikhila Khanna, Megha Lovejan, Mujeeb Rahiman K. M., Harikrishnan Mahadevan   +7 more
wiley   +1 more source

Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni [PDF]

, 2016
Detailed gel images of the differential spots identified by mass spectrometry and database search. Magnification of the 2D gel-areas corresponding to the 19 differentially expressed spots identified by mass spectrometry and database search.
Alba Cortés, Carla Muñoz-Antolí, J. Guillermo Esteban, Javier Sotillo, María Trelis, Rafael Toledo   +5 more
core   +5 more sources

Molecular cloning and characterization of growth factor receptor bound-protein in Clonorchis sinensis. [PDF]

PLoS ONE, 2014
BACKGROUND: Clonorchis sinensis causes clonorchiasis, a potentially serious disease. Growth factor receptor-bound protein 2 (Grb2) is a cytosolic protein conserved among animals and plays roles in cellular functions such as meiosis, organogenesis and ...
Xuelian Bai, Ji-Yun Lee, Tae Im Kim, Fuhong Dai, Tae-Jin Lee, Sung-Jong Hong   +5 more
doaj   +1 more source