Results 101 to 110 of about 169,996 (318)
ESC Heart Failure, EarlyView.Impact of empagliflozin in patients with and without T2D or CKD in the EMPACT‐MI trial. Baseline characteristics, HF outcomes and subgroup analysis of efficacy endpoints are shown. # Hazard ratios estimated via Cox proportional hazard model (unless indicated otherwise). ^ Rate ratios via negative binomial regression.
Francesco Fioretti +23 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Background Galectin‐3 (Gal‐3) is a circulating biomarker of fibrosis, with higher levels being associated with an increased risk of progression of heart failure and kidney disease. Patients with type 2 diabetes mellitus (T2DM) are at increased risk of both.
Paul M. Haller +12 more
wiley +1 more source
Evaluation ofAaspirin, Clopidogrel or Their Combination In Hypertensive Patients
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2010 The objective of this study is to evaluate the effect of aspirin, clopidogrel or their combination on different parameters in hypertensive patients.
Fadia Y. Al-hamdani +1 more
doaj +1 more source
European Heart Journal - Cardiovascular Pharmacotherapy, 2019 AIMS Clopidogrel is prescribed for the prevention of atherothrombotic events. While investigations have identified genetic determinants of inter-individual variability in on-treatment platelet inhibition (e.g.
J. Lewis +45 more
semanticscholar +1 more source
Acute hemichorea‐hemiballism as the initial sign of cortical cerebral infarction: A case report
Neuroprotection, EarlyView.Abstract Hemichorea‐hemiballism is classically associated with the contralateral basal ganglia, particularly involving the putamen and subthalamic nucleus, whereas cortical involvement remains a rare etiology. In this case, we present a patient with acute hemichorea‐hemiballism secondary to multiple cortical infarcts demonstrated by neuroimaging.
Jin Xiong +5 more
wiley +1 more source
Buffer‐Mediated Catalyst‐Free Strecker Reaction Toward Enzymatic Implementation
ChemistryOpen, EarlyView.Hydroxynitrile lyases (HNLs) are proven to accept imines as substrates and to catalyze the formation of α‐aminonitriles. The process results in the precursors of natural and unnatural α‐amino acids after extraction, without chromatography. This new application of HNL enzymes in Strecker reaction is an example for biocatalysis in multicomponent ...
Péter Magyar +8 more
wiley +1 more source
A Dose‐Aware Model for Revealing Dose‐Risk Relationship of Drug–Drug Interaction
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Drug–drug interaction (DDI) is a common cause of adverse drug events (ADEs). Despite real‐world data‐based studies have developed knowledge on DDI, the precise relationships between doses of two‐drug combinations exposure and the risks of ADEs remain largely unknown.
Yi Shi +8 more
wiley +1 more source
Veterinary Record Case Reports, EarlyView.Abstract This report describes the diagnosis, treatment and long‐term follow‐up of a dog with hepatic arteriovenous malformation and extensive thrombus of the splanchnic vessels. A 1‐year‐old, male, neutered golden retriever presented with haematochezia and ascites.
Yuqing Sun +2 more
wiley +1 more source
Rare but relevant: Cannabis use and myocardial infarction
Addiction, EarlyView.Abstract Pre‐clinical research and case reports have linked cannabis use to myocardial infarction (MI) since the 1970s. The association with MI may be specific to certain types and patterns of cannabis use as well as certain consumer characteristics; however, due to limited data availability, meta‐analyses examining the association between cannabis use
Prianka Padmanathan, Emmert Roberts
wiley +1 more source
Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper
Allergy, EarlyView.ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini +10 more
wiley +1 more source