Results 181 to 190 of about 148,561 (252)

Antithrombotic Therapy in Primary and Secondary Prevention of Coronary Artery Disease. [PDF]

J Clin Med
Di Leo G, Spagnolo M, Giacoppo D, Greco A, Capodanno D.   +4 more
europepmc   +1 more source

Assessing Functional Recovery in Ischemic Stroke: An Observational Study of Dual vs. Single Antiplatelet Therapy in Indian Patients

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aim In an aging population, stroke is a leading cause of morbidity and mortality. More than 80% of stroke cases in the elderly are ischemic strokes. Stroke is the sixth most common cause of disability globally and the second most common cause after ischemic heart disease (IHD).
Sohailuddin Mohammad, Hemaakshi Gupta, Dipinder Deep Bhat, Tirunagari Navya Sree, Anveshak, Summaiah Asim, Mohammed Faizan Ahmed, Pooja Pancholi, Younes Nabgouri, Mohammed Abdul Mateen, Nagham Al Dirani   +10 more
wiley   +1 more source

Measurement of Active Thrombin Bound to Circulating D‐Dimers as a Sensitive Biomarker for Prothrombotic Conditions

Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
Scheme of preparation of D‐dimers and evaluation of D‐dimer‐bound thrombin activity. Thrombin bound to fibrin participates in ongoing fibrinogen transformation and its inhibition is impeded. Our detection system may aid in identifying patients at risk of recurrent thrombotic events or complications, regardless of the origin of the acute health problem.
Jana Stikarova, Leona Chrastinova, Kristyna Svobodova, Marek Havlicek, Jan Louzil, Eliska Ceznerova, Alzbeta Hlavackova, Ondrej Pastva, Pavla Pecherkova, Ingrid Hrachovinova, Ondrej Kucerka, Roman Kotlin, Petr Soukup, Peter Salaj, Martin Maly, Jiri Suttnar   +15 more
wiley   +1 more source

A case report and literature review of proton pump inhibitors inducing insulin autoimmune syndrome. [PDF]

Front Endocrinol (Lausanne)
Zhang W, Wen J, Qi S, Zhang G, Yang X, Zeng L, Xu W, Deng H.   +7 more
europepmc   +1 more source

The Dilution Paradox in Extracellular Vesicle Flow Cytometry

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Concentrations of extracellular vesicles (EVs) can be measured by flow cytometry, which detects fluorescence and light scattering signals from single particles. To ensure single particle detection, plasma samples are diluted based on their particle concentration, which can differ 100‐fold between samples.
Joyce Rops, Naomi Buntsma, Aleksandra Gąsecka, Leonie de Rond, Anne Yaël Nossent, Nyika D. Kruyt, Rienk Nieuwland, Edwin van der Pol   +7 more
wiley   +1 more source

Continuous Subcutaneous Ketamine Infusion May Induce Tacrolimus and Sirolimus Clearance: A Case Report

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Drug interactions involving immunosuppressants can compromise transplant outcomes. Although repeated ketamine administration induces hepatic enzymes in experimental models, clinical reports of induced clearance of cytochrome P450 (CYP) substrates are lacking. Continuous subcutaneous ketamine infusions are increasingly used for acute
Jana Stojanova, Bridin Murnion, Fay Burrows, Lilibeth Carlos, Tomoyuki Mizuno, Takanobu Nadai, Kei Irie, Nuala Helsby, Kavitha Muthiah, Richard Day   +9 more
wiley   +1 more source

Is Aspirin Still Indispensable After PCI-Rethinking Dual Antiplatelet Therapy in Contemporary Practice. [PDF]

J Cardiovasc Dev Dis
Yadav K, Ahmed SES, Abdelgader M, Khalid R, Veerasamy M, Das A, Bulluck H.   +6 more
europepmc   +1 more source

Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals

Aging Cell, Volume 25, Issue 6, June 2026.
Supplement users have lower epigenetic biological age than non‐users. Several supplements or supplement classes are associated with some benefit on epigenetic age in either cross‐sectional or longitudinal analyses. ABSTRACT In this cross‐sectional cohort we analyzed data from 4260 “health enthusiasts” who purchased at least one saliva‐based DNA ...
Kamil Pabis, Weilan Wang, Kumar Selvarajoo, Yelena V. Budovskaya, Vincenzo Sorrentino, Jan Gruber, Brian K. Kennedy   +6 more
wiley   +1 more source

Prevalence of Potentially Inappropriate Apixaban Prescribing Within a Single‐Centre Tertiary Hospital

Australasian Journal on Ageing, Volume 45, Issue 2, June 2026.
ABSTRACT Objective Apixaban is widely recommended as first line therapy for atrial fibrillation (AF) and venous thromboembolism (VTE). Despite the widespread availability of dosing guidelines, anecdotal evidence suggests clinicians do not routinely follow these recommendations. Inappropriate dose reduction is associated with suboptimal patient outcomes.
Katherine J. Creeper, Grace Lenaghan, Aaron Stockwell, Matthew Schmidt, Katharine Ingram, Andrew C. Stafford   +5 more
wiley   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source