Results 71 to 80 of about 169,996 (318)
Frontiers in Veterinary Science, 2020 The primary objective of this study was to evaluate a novel flow cytometry-based assay of quantifying platelet phosphorylation of vasodilator-stimulated phosphoprotein (P-VASP) in cats that received clopidogrel treatment.
Ronald H. L. Li +3 more
doaj +1 more source
Journal of the American College of Cardiology, 2011 Multidrug therapy increases the risk for drug-drug interactions. Clopidogrel, a prodrug, requires hepatic cytochrome P450 (CYP) metabolic activation to produce the active metabolite that inhibits the platelet P2Y₁₂ adenosine diphosphate (ADP) receptor, decreasing platelet activation and aggregation processes. Atorvastatin, omeprazole, and several other
Division of Cardiovascular Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan ( host institution ) +3 more
openaire +4 more sources
Atorvastatin–Clopidogrel Interaction [PDF]
Circulation, 2003 To the Editor: We read with some fascination the paper by Lau et al1 exploring the possibility of an interaction between atorvastatin and clopidogrel. Unfortunately, the authors do not make clear whether the patients in the first study received aspirin, which would be the normal standard of care in patients undergoing percutaneous coronary ...
Russell A. Denman, Paul T. Martin
openaire +3 more sources
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Dual antiplatelet therapy (DAPT) is recommended after percutaneous coronary intervention (PCI), though the optimal duration is unclear. DAPT reduces stent thrombosis, repeat myocardial infarction, and cardiovascular death, though at the cost of increased bleeding events.
Thomas Fretz +10 more
wiley +1 more source
Ендоваскулярна нейрорентгенохірургія, 2020 Objective – to study the result of light transmission aggregometry with ADP for platelet reactivity before and after clopidogrel administration before extra-intracranial stenting. Materials and methods.
D.V. Shchehlov +3 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT We aimed to compare the long‐term efficacy and safety of drug‐coated balloon (DCB) and drug‐eluting stent (DES) following atherectomy for coronary arteries with severely calcified lesions. Of the 258 consecutive patients and 422 de novo lesions treated with DCB at Kanazawa Medical University Hospital, we retrospectively enrolled highly ...
Taka‐aki Takamura +11 more
wiley +1 more source
Optical Coherence Tomography for Cervical Artery Dissection
Annals of Neurology, EarlyView.
Guangxun Shen +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.This study assessed the use of 35 pharmacogenomic (PGx) medications listed in the Royal College of Pathologists of Australasia (RCPA) guideline, estimated the potential costs of subsidizing PGx testing in Australia, and predicted related prescribing changes.
Bella D. Ianni +3 more
wiley +1 more source
Therapeutics and Clinical Risk Management, 2015 Yolande B Saab,1 Rony Zeenny,2 Wijdan H Ramadan2 1School of Pharmacy, Pharmaceutical Sciences Department, 2School of Pharmacy, Pharmacy Practice Department, Lebanese American University, Byblos, Lebanon Purpose: Response to clopidogrel varies widely with
Saab YB, Zeenny R, Ramadan WH
doaj
Effect of obesity and serum leptin level on clopidogrel resistance
Türk Kardiyoloji Derneği Arşivi, 2016 Objective: Clopidogrel inhibits platelet aggregation by blockade of platelet adenosine diphosphate (ADP) P2Y12 receptor. Leptin is the obesity gene product, and its serum level increases with obesity.
Ali Dogan +5 more
doaj +1 more source