Results 71 to 80 of about 141,477 (341)
Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy
Journal of the Formosan Medical Association, 2012 Clopidogrel is associated with a high incidence of upper gastrointestinal bleeding in high-risk patients. However, the characteristic upper gastrointestinal lesions in symptomatic clopidogrel users remain unclear.
Tzung-Jiun Tsai +14 more
doaj +1 more source
rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]
, 2014 BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy +4 more
core +3 more sources
JAMA Neurology, 2019 Importance Dual antiplatelet therapy with clopidogrel and aspirin is effective for secondary prevention after minor ischemic stroke or transient ischemic attack (TIA).
Yuesong Pan +13 more
semanticscholar +1 more source
Sheep femoral artery occlusion is well tolerated and does not result in ischemia
Animal Models and Experimental Medicine, EarlyView.Left femoral artery occlusion (yellow arrows) can be seen shortly after the lateral femoral circumflex artery origin, with distal arterial reconstitution. Sheep with femoral artery occlusion showed no change in pain scores nor mobility, thus making them an appropriate model for novel small diameter femoral artery graft studies. Abstract Objective Sheep
Timothy Shiraev +10 more
wiley +1 more source
Anti-platelet therapy: ADP receptor antagonists. [PDF]
, 2011 The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD
core +2 more sources
An Idiosyncratic Reaction to Clopidogrel [PDF]
The Permanente Journal, 2015 Clopidogrel is an irreversible antiplatelet agent belonging to the thienopyridine group that acts to antagonize the adenosine diphosphate P2Y12 receptor on platelets. It thus inhibits the activation of platelet glycoprotein GPIIb/IIIa complex, which is essential for fibrinogen—platelet complex formation.
Kapila, Aaysha +6 more
openaire +4 more sources
The Effect of Oscimum Sanctum to the Thrombocytes Number on Mice [PDF]
, 2016 Oscimum sanctum is herbal that was spread widely in Indonesia. Oscimum sanctum contains abundant of substances. One of the functions on Oscimum sanctum was anti-thrombocytes effect. This effect is associated with platelet function as a mechanical plug in
Astuti, Y. (Yoni), Wijayanti, R. (Rum)
core
Cypc19*17 Polymorphism as a Risk-factor for Nsaids-induced Ulcers [PDF]
, 2016 The new risk-factors for peptic ulcers induced by the use of nonsteroidal antiinflammatory drugs, such as polymorphism of different isoenzymes of cytochrome P450 were considered in the article.
Balabanseva, A. (Alexandra) +2 more
core +2 more sources
Effect of clopidogrel added to aspirin in patients with atrial fibrillation.
New England Journal of Medicine, 2009 BACKGROUND Vitamin K antagonists reduce the risk of stroke in patients with atrial fibrillation but are considered unsuitable in many patients, who usually receive aspirin instead.
S. Connolly +6 more
semanticscholar +1 more source
Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy
Advanced NanoBiomed Research, EarlyView.This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai +5 more
wiley +1 more source