Results 111 to 120 of about 3,779 (175)

SYNTHESES OF PGF2α AND CLOPROSTENOL

Tetrahedron, 1981
Abstract Prins reaction of norbornadiene leads to an efficient synthesis of the ketoacid ( 5 ) which is cleaved regio- and stereo-specifically with acids to 5- exo -substituted norbornan-2-one-7-carboxylic acids. Baeyer-Villiger oxidation of these ketones leads to bridged lactones, e.g.
N.R.A. Beeley, R. Peel, J.K. Sutherland, J.J. Holohan, K.B. Mallion, G.J. Sependa   +5 more
openaire   +1 more source

Farrowing induction with cloprostenol-xylazine combination

Theriogenology, 1989
Eighty crossbred, multiparous sows, weighing between 190 and 320 kg, were randomly assigned to the following four treatment groups of 20 sows each: 1) saline-saline, 2) cloprostenol-saline, 3) saline-xylazine and 4) cloprostenol-xylazine. The mean gestation length of each multiparous sow was calculated.
Walter H Hsu
exaly   +3 more sources

Double bond isomers of cloprostenol

Prostaglandins, 1979
The syntheses of five compounds isomeric with the potent luteolytic agent cloprostenol are described. These are the trans-delta 5, cis and trans-delta 4, cis-delta 6 (methyl ester) and cis-delta 13 analogues. The cis-delta 4 isomer is as potent as cloprostenol as a luteolytic agent in hamsters but the others are markedly less so.
J, Bowler, E D, Brown, N S, Crossley, D W, Heaton, T J, Lilley, N, Rose   +5 more
openaire   +2 more sources

Induction of Parturition in Cattle with Cloprostenol

British Veterinary Journal, 1982
SUMMARY Four cows were induced to calve prematurely by a continuous intravenous infusion of cloprostenol, a prostaglandin analogue, and 64 cows and heifers were induced by a single intramuscular injection. No advantage was evident from the continuous administration of cloprostenol compared with the single injection.
C T, Johnson, P S, Jackson
openaire   +2 more sources

HPLC method for enantioselective analysis of cloprostenol

Journal of Pharmaceutical and Biomedical Analysis, 2008
A new HPLC method for the separation and quantification of cloprostenol enantiomers was developed. The optimized separation system consisted of Chiralcel OD-RH column and acetonitrile-sodium dihydrogenphosphate (pH 3.0; 20mM) (33:67, v/v) as the mobile phase.
Květa Kalikova, Eva Tesarova, Zuzana Bosáková   +2 more
exaly   +3 more sources

Induction of ovulation in gilts with cloprostenol

Theriogenology, 1989
Prepuberal gilts were treated with 750 IU pregnant mare serum gonadotropin (PMSG) followed 72 h later by 500 IU human chorionic gonadotropin (hCG) to induce follicular growth and ovulation. In this model, ovulation occurred at 42 +/- 2 h post hCG treatment.
A, Srikandakumar, B R, Downey
openaire   +2 more sources

Fluorine containing analogues of cloprostenol

Journal of Fluorine Chemistry, 2020
Abstract The reaction of methyl ester C-11, C-15 bis-TBDPS derivative of cloprostenol with DAST in CH2Cl2 at −78 °C followed by warming to room temperature results in a product of SN2-substitution at C-9, elimination to give a Δ8,9-olefine, and epimeric 9-deoxy-C-8 fluorides. The reaction products were separated by TLC and HPLC methods.
Nikolay S. Vostrikov, Vadim V. Zagitov, Sergei P. Ivanov, Alexander N. Lobov, Svetlana F. Gabdrakhmanova, Mansur S. Miftakhov   +5 more
openaire   +1 more source