Results 101 to 110 of about 289,709 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A new closed-form solution for optimal portfolio selection with liquidity risk

Mathematical Modelling and Analysis
In the literature on optimal portfolio selection problems, it is rare that closed-form solutions are found. It is even more so when liquidity risk needs to be taken into consideration.
Dhruv Goel, Song-Ping Zhu
doaj   +1 more source

An Efficient Closed Form Solution to the Absolute Orientation Problem for Camera with Unknown Focal Length. [PDF]

Sensors (Basel), 2021
Guo K, Ye H, Zhao Z, Gu J.
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Validation of a closed-form solution to Fick’s diffusion laws for non-steady state sorption by a plane sheet

Results in Engineering
Fick's second law is a partial differential equation that describes the time-dependent concentration distribution of a diffusing species. It is fundamental to fields like environmental and materials engineering.
Michael Brilz, Senmiao Zhang, Holger Hoche, Matthias Oechsner   +3 more
doaj   +1 more source

Construct the closed-form solution of -net of Petri nets by case study

Advances in Mechanical Engineering, 2017
After our researches on the effect of a non-sharing resource in a k th order which is the concept of customization manufacturing, in this article we extend the research on the closed-form solution of control-related states to the so-called A -net which ...
Daniel Yuh Chao, Tsung Hsien Yu
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Elastic Contact Between a Transversely, Uniformly Loaded Circular Membrane and a Spring-Reset Rigid Flat Circular Plate: An Improved Closed-Form Solution

Mathematics
The closed-form solution of the problem regarding elastic contact between a transversely, uniformly loaded circular membrane and a spring-reset rigid flat circular plate has potential application value in sensor developments or bending-free shell designs,
Xiao-Ting He, Jing-Miao Yin, Jun-Song Ran, Jun-Yi Sun, Ying Guo   +4 more
doaj   +1 more source