Results 61 to 70 of about 744 (275)

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Enrichment of impurities seeded for exhaust control in a spherical tokamak power plant geometry

Nuclear Fusion
Through SOLPS-ITER simulations, we have investigated the ability of seeded argon and neon impurities to effectively control divertor power loading in a power-plant-class spherical tokamak geometry.
S.L. Newton, R.T. Osawa, S.S. Henderson, D.J. Moulton, O. Myatra, V. Badicel   +5 more
doaj   +1 more source

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

Advanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu, Yulu Yang, Zhiqi Hao, Jing Xu, Huibo Zhao, Qiang Zhang, Deyong Ren, Xia Li, Guojun Dong, Lan Shen, Li Zhu, Jiang Hu, Zhenyu Gao, Qing Li, Qian Qian, Guangheng Zhang   +15 more
wiley   +1 more source

Poloidal pressure gradients, divertor detachment and marfes

, 1997
Because the radiation power density from a marfe scales approximately as the square of its plasma pressure, and since increased radiation would aid divertor detachment for high power tokamaks, this paper identifies regions that might permit locally ...
Schaffer, M.J., M. J. Schaffer
core   +1 more source

An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots

Advanced Science, EarlyView.
This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang, Tao Jiang, Zhongyue Lu, Dapeng Fan, Zucheng Yi, Zirong Luo   +5 more
wiley   +1 more source

Interpretive modeling of tungsten divertor leakage during experiments with neon gas seeding

Nuclear Fusion
Many existing and future tokamaks with tungsten divertors operate, or will operate, with low- Z impurity seeding, but the direct effect of these seeded impurities on tungsten Scrape-off-Layer (SOL) transport has not been explored in detail.
Matthew S. Parsons, Gregory Sinclair, Tyler Abrams, Patrick Byrne, Colin Chrystal, Florian Effenberg, Jeffrey L. Herfindal, Tomas Odstrcil, Robert S. Wilcox   +8 more
doaj   +1 more source

Collector probe analysis of tungsten transport to the far-SOL from the DIII-D SAS-VW divertor experiment

Nuclear Materials and Energy
Experimental results from the 2022 tungsten (W)-coated Small Angle Slot (SAS-VW) divertor campaign at DIII-D coupled with interpretive 3DLIM modelling show opposing trends for core impurity content when compared to impurity deposition on far-Scrape Off ...
S.H. Messer, J.D. Mateja, J.H. Nichols, A. Cacheris, J.D. Duran, S.A. Zamperini, G. Sinclair, D. Donovan, T. Abrams, T. Odstrcil, J. Ren, W. Garcia, E.A. Unterberg, P.C. Stangeby, D.L. Rudakov, J.D. Elder, J. Watkins   +16 more
doaj   +1 more source

Helical Divertor in the Large Helical Device

, 1992
"The Large Helical device (LHD), now under construction is a Heliotron/torsatron device with a closed divertor system. The edge LHD magnetic structure has been studied in detail. A peculiar feature of the configuration is existence of edge surface layers,
Hantao, Ji, Noda, N., Akaishi, K., Akao, H., Watanabe, T., Sagara, A.", "Ohyabu, N., Kawamura, T., Kubota, Y., Yamazaki, K., Kaneko, H., Morimoto, S., Ono, T., Motojima, O.   +13 more
core  

PancDS in Real‐World Practice: A Prospective Multicenter Validation of a Clinical Decision‐Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis

Advanced Science, EarlyView.
A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang, Weinuo Qu, Wenwen Cai, Chuhuai Wang, Chenxi Lyu, Qingguo Xie, Qian Chu, Yaqi Shen, Peng Xiao, Feng Li, Qingpeng Zhang, Jiali Li, Jeong Min Lee, Zhen Li   +13 more
wiley   +1 more source

Particle control in the DIII-D advanced divertor [PDF]

, 1991
A new, electrically biasable, semi-closed divertor was installed and operated in the D3-D lower outside divertor location. The semi-closed divertor has yielded static gas pressure buildups in the pumping plenum in excess of 10 mtorr.
Hill, D. N., Lippmann, S. I., Mahdavi, M. A., Petrie, T. W., Schaffer, M. J., Klepper, C. C., Rensink, M., Hogan, J., Mioduszewski, P., Owen, L., Buchenauer, D., Stambaugh, R. D.   +11 more
core   +2 more sources