Results 81 to 90 of about 131,470 (252)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Expected Closeness or Mobilisation: Why Do Voters Go to the Polls? Empirical Results for Switzerland, 1981 – 1999 [PDF]

open access: yes
Using data of Swiss referenda from 1981 to 1999, this paper presents new empirical results which allow us to discriminate better between the decision and mobilisation hypotheses of electoral participation.
Tobias Schulz, Gebhard Kirchgässner
core  

Closeness discrepancies in couple relationships

open access: yes, 2021
Close relationships with others are a central part of human experience and play an important role in individuals’ mental as well as physical health (Holt-Lunstad, Smith, & Layton, 2010).
Sebastian Pusch
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Suppress the diffusion of rumors with nodes closeness mining

open access: yes网络与信息安全学报, 2016
Through making the analysis of information spread in social networks,the supression of rumors,error information and other negative information was realized.Firstly,by analyzing the structure of social networks and the characteristics of node behavior,a ...
Ya-ping TIAN,Li YANG,Xiao-qin WANG,Ya-feng QIAO
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Digital technologies, closeness, and practices of being together in the context of the new normal in Serbia [PDF]

open access: yesGlasnik Etnografskog Instituta SANU
At the beginning of 2020, the global community faced a dramatic collapse of everyday life due to the pandemic caused by the emergence of a new coronavirus.
Radivojević Sonja
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Les associations foncières pastorales : un dispositif de gouvernance concrète du foncier dans les territoires de montagne

open access: yesEchoGéo, 2018
The pastoral land associations are tools of land restructuring created by the pastoral law of 1972 to propose a solution to the specific problems of the land in mountain (division, joint possessions, absentee owners).
Laurence Barthe, Corinne Eychenne
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy