Results 121 to 130 of about 71,434 (279)
Degree Centrality, Betweenness Centrality, and Closeness Centrality in Social Network [PDF]
Proceedings of the 2017 2nd International Conference on Modelling, Simulation and Applied Mathematics (MSAM2017), 2017 Yu Luo, Junlong Zhang
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Closeness Centrality of Cycle and Corona Product Graphs: Application in Fuzzy Transportation Network
Transactions on Fuzzy Sets and SystemsCentrality measurement is a useful way to find the most important points (vertices) and connections (edges) in a network. Over time, many researchers have created different types of centrality measures to study and understand how ...
Shaoli Nandi +2 more
doaj
Modeling Minneapolis Skyway Network [PDF]
Adopting an agent-based approach, this paper explores the topological evolution of the Minneapolis Skyway System from a microscopic perspective. Under a decentralized decision-making mechanism, skyway segments are built by self-interested building owners.
Arthur Huang, David Levinson
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
An analysis of research trends of the Asian Journal of Shipping and Logistics
Asian Journal of Shipping and LogisticsThe analysis of research trends in papers published in academic journals can help establish the identity of a field by discovering the research content and characteristics conducted from the past to the present.
Maria Listan Bernal +4 more
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