Results 61 to 70 of about 175,302 (247)
Closeness Centrality of Asymmetric Trees and Triangular Numbers
MathematicsThe combinatorial problem in this paper is motivated by a variant of the famous traveling salesman problem where the salesman must return to the starting point after each delivery.
Nytha Ramanathan +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Network characteristics and patent value-Evidence from the Light-Emitting Diode industry. [PDF]
PLoS ONE, 2017 This study proposes a different angle to social network analysis that evaluates patent value and explores its influencing factors using the network centrality and network position.
Way-Ren Huang +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Visualisasi Pemain Sepak Bola Indonesia pada DBPedia dengan menggunakan Node2Vec dan Closeness Centrality [PDF]
, 2020 . Visualization of Indonesian Football Players on DBpedia through Node2Vec and Closeness Centrality Implementation. Through Semantic Web, data available on the internet are connected in a large graph.
Ardha Perwiradewa +5 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Scale-dependent measure of network centrality from diffusion dynamics
Physical Review Research, 2020 Classic measures of graph centrality capture distinct aspects of node importance, from the local (e.g., degree) to the global (e.g., closeness). Here we exploit the connection between diffusion and geometry to introduce a multiscale centrality measure. A
Alexis Arnaudon +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The dynamics of closeness and betweenness [PDF]
Although both betweenness and closeness centrality are claimed to be important for the effectiveness of someones network position, it has not been explicitly studied which networks emerge if actors follow incentives for these two positional advantages ...
Vincent Buskens, Berno Buechel
core
Computing Classic Closeness Centrality, at Scale
, 2014 Closeness centrality, first considered by Bavelas (1948), is an importance measure of a node in a network which is based on the distances from the node to all other nodes.
Renato F. Werneck +3 more
core +1 more source