Results 101 to 110 of about 38,675 (255)

The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection and relapses

open access: yesMicrobiologyOpen, 2020
Clostridioides difficile infection (CDI) represents an important health problem worldwide, with significant morbidity and mortality. This infection has also high recurrence rates, whose pathophysiological grounds are still poorly understood. Based on our
Gabrio Bassotti   +3 more
doaj   +1 more source

New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria [PDF]

open access: yes, 2017
Multidrug resistance (MDR) has appeared in response to selective pressures resulting from the incorrect use of antibiotics and other antimicrobials.
Amaral, Leonard   +3 more
core   +2 more sources

Bile Acids as Key Mediators of the Gut Microbiota–Immune Axis: Potential Biomarker and Therapeutic Perspectives

open access: yesBioFactors, Volume 52, Issue 1, January/February 2026.
Primary bile acids synthesized in the liver are transformed by gut microbes into secondary bile acids that engage receptors such as FXR and TGR5, thereby modulating immune function and metabolic homeostasis. Dysregulation of these signaling pathways contributes to MASH, NAFLD, IBD, and neurodegenerative disorders, underscoring their relevance as ...
Simone Baldi   +5 more
wiley   +1 more source

Concurrent and Subsequent Co-Infections of Clostridioides difficile Colitis in the Era of Gut Microbiota and Expanding Treatment Options [PDF]

open access: gold, 2022
Mattia Trunfio   +5 more
openalex   +1 more source

Decreases in Antimicrobial Use Associated With Multihospital Implementation of Electronic Antimicrobial Stewardship Tools. [PDF]

open access: yes, 2020
BackgroundAntimicrobial stewards may benefit from comparative data to inform interventions that promote optimal inpatient antimicrobial use.MethodsAntimicrobial stewards from 8 geographically dispersed Veterans Affairs (VA) inpatient facilities ...
Butler, Jorie M   +10 more
core   +1 more source

Exploring Fecal Microbiota Transplantation: Potential Benefits, Associated Risks, and Challenges in Cancer Treatment

open access: yesCancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Fecal microbiota transplantation (FMT) has emerged as a groundbreaking strategy for modulating the gut microbiome and improving cancer treatment outcomes. This review synthesizes the current evidence on the role of FMT in oncology, focusing on its potential to enhance the efficacy of immunotherapy, restore microbiome homeostasis ...
Aswathi Ramesh   +3 more
wiley   +1 more source

Glucomannan from Dendrobium officinale Alleviates Colitis via Modulating Gut Microbiota and Upregulating Deoxycholic Acid Production

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Dietary fiber is a bioactive substance that can modulate gut microbiota and exert a relieving effect on inflammatory bowel disease (IBD). Dendrobium officinale polysaccharide (DOP) is a type of bioactive dietary fiber that has been proven to have various biological activities on intestinal function.
Jie Xu   +7 more
wiley   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

open access: yesMedicine Bulletin, Volume 2, Issue 1, Page 94-123, January 2026.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng   +8 more
wiley   +1 more source

Programming the Infant Gut: How Maternal and Early Life Nutrition Shape the Infant Microbiome and Long‐term Health—A Narrative Review

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
Good nutrition in pregnancy and early life plays a key role in shaping the offspring gut microbiota, which supports healthy growth, immune maturation, and neurodevelopment. Poor maternal and early‐life diets can disrupt this process, increasing the risk of obesity, undernutrition, and disease later in life.
Fanette Fontaine   +5 more
wiley   +1 more source

Clostridioides difficile Infection

open access: yesClinics in Colon and Rectal Surgery, 2020
Linda, Ferrari, Alessandro, Fichera
openaire   +5 more sources

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