Results 211 to 220 of about 25,400 (245)
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Microscopy methods for Clostridioides difficile
AnaerobeMicroscopic technologies including light and fluorescent, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and cryo-electron microscopy have been widely utilized to visualize Clostridioides difficile at the molecular, cellular, community, and structural biology level. This comprehensive review summarizes the microscopy tools (
Chenlin Hu, Kevin W. Garey
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Clostridioides (Clostridium) difficile
2021This chapter evaluates Clostridioides (Clostridium) difficile, a gram-positive anaerobic spore-forming bacillus found in colon flora. When C. difficile is induced to produce exotoxins (A/B) symptomatic disease (i.e., diarrhea/colitis) follows. The clinical spectrum of infection ranges from watery toxigenic diarrhea to invasive transmural colitis.
Cheston B. Cunha, Burke A. Cunha
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Comparative Genomics of Clostridioides difficile
Clostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of nosocomial diarrhoea in hospitals. The availability of large numbers of genome sequences, mainly due to the use of next-generation sequencing methods, has undoubtedly shown their immense advantages in the determination of C ...Sandra, Janezic +2 more
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Diagnosis and Management of Clostridioides difficile
American Journal of GastroenterologyClostridioides difficile infection (CDI) is challenging to diagnose and treat. Recently published studies and clinical observations have improved our understanding around diagnostic testing and positioning of antibiotics and microbiota-based therapies.
Colleen R. Kelly, Paul Feuerstadt
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Foodborne transmission of Clostridioides difficile
Current Opinion in Gastroenterology, 2020The epidemiology of Clostridioides difficile infection (CDI) is changing, with increasing rates of community-acquired infections. In light of recent advances in understanding C. difficile transmission networks with whole-genome sequencing, new routes of spread outside the hospital need to be considered.
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Antibiotic Resistances of Clostridioides difficile
The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile infections (CDIs) are a matter of concern for public health. Antibiotic resistance plays an important role in driving C. difficile epidemiology.Patrizia, Spigaglia +2 more
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Clostridioides difficile Infections: Prevention and Treatment Strategies
Clostridioides difficile is the most common causative agent of antibiotic-associated diarrhea. This spore forming, obligate anaerobic, gram-positive bacillus is becoming responsible for an increasing number of infections worldwide, both in community and in hospital settings, whose severity can vary widely from an asymptomatic infection to a lethal ...Levy, Elvira Ingrid +3 more
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The prognostic value of toxin B and binary toxin in Clostridioides difficile infection
Gut Microbes, 2021Salvador López-Cárdenas +2 more
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