Results 1 to 10 of about 54,164 (265)

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

Nature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh, In Young Hwang, Hui Ling Lee, Ryan De Sotto, Jonathan Wei Jie Lee, Yung Seng Lee, John C. March, Matthew Wook Chang   +7 more
doaj   +2 more sources

Extraintestinal Clostridioides difficile infection

IDCases, 2020
Clostridioides (Clostridium) difficile is the major cause of healthcare antibiotic-associated diarrhoea. However, extra-intestinal manifestations of Clostridioides (Clostridium) difficile infection (CDI) (including bacteremia and tissue infection) are ...
Zhao Hai, Lei Peng Zhen, Ma Juan, Yang Fan, Cang Jin Rong, Liang Jing Yao, Zhang Li Xia   +6 more
doaj   +3 more sources

Cutting edges in Clostridioides difficile infections

Swiss Medical Weekly, 2021
Clostridioides difficile is the most common cause of hospital-acquired diarrhoea and one of the most important causes of hospital-acquired infections.
Ana Durovic, Sarah Tschudin-Sutter
doaj   +3 more sources

The Impact of Diet on Clostridioides difficile Infection: A Review. [PDF]

J Infect Dis
Clostridioides difficile poses a significant public health challenge as it is the leading cause of antibiotic-associated diarrhea and is associated with significant morbidity and mortality.
Castro M, Silver HJ, Hazleton K, Lozupone C, Nicholson MR.   +4 more
europepmc   +2 more sources

Incidence of hospital-acquired toxin-producing clostridioides difficile infection between the pre-pandemic (2017–2019) and pandemic (2020–2022): a retrospective cohort study [PDF]

Archives of Public Health
Background In 2020, the World Health Organization declared SARS-CoV-2 a global public health emergency. Healthcare systems were forced to reorganize care delivery and implement wide-ranging infection control strategies. Among hospital-acquired infections,
Raquel García Rodríguez, María José Pereira Rodríguez, Alejandra Pilar García López, Fabián Freijedo Fariñas, Angela Nogueira Gómez   +4 more
doaj   +2 more sources

Clostridioides difficile infection: an update.

Infezioni in Medicina
Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment ...
Federica Salvati, Francesca Catania, Rita Murri, M. Fantoni, Carlo Torti   +4 more
semanticscholar   +3 more sources

Clostridioides difficile infections: Preventive strategies [PDF]

, 2023
Clostridioides difficile infections primarily affect elderly, hospitalised patients treated with antibiotics and are among the most common healthcare-related infections. This thesis aimed to improve the understanding of the best prevention strategies for
Edman Wallér, Jon
core   +2 more sources

Oral Vancomycin for Prevention of Recurrent Clostridioides difficile Infection: A Randomized Clinical Trial.

JAMA Netw Open
This randomized clinical trial examines whether prophylactic oral vancomycin vs placebo reduces recurrent Clostridioides difficile infection in adults receiving antibiotics for another indication.
Keating JA, Xu T, Graham MB, Ramesh M, Khanna S, Dixon J, Kates A, Haight K, Zhao J, Saddler C, Safdar N.   +10 more
europepmc   +2 more sources

Clostridioides difficile Infection: Diagnosis and Treatment Challenges

Pathogens
Clostridioides difficile is the most important cause of healthcare-associated diarrhea in the United States. The high incidence and recurrence rates of C.
John E Markantonis, John T. Fallon, R. Madan, Md Zahidul Alam   +3 more
semanticscholar   +4 more sources

Editorial: Clostridioides difficile infection

Frontiers in Medicine
Guido Granata, Frédéric Barbut, Nicola Petrosillo   +2 more
doaj   +3 more sources