Results 41 to 50 of about 1,849,474 (227)

European Society of Clinical Microbiology and Infectious Diseases: 2021 update on the treatment guidance document for Clostridioides difficile infection in adults. [PDF]

, 2021
SCOPE: In 2009, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) published the first treatment guidance document for Clostridioides difficile infection (CDI). This document was updated in 2014.
Guery, B., Wilcox, M.H., Hristea, A, Goorhuis, A, Tschudin-Sutter, S, Kuijper, E J, Coia, J; id_orcid, Bouza, E, van Rossen, T.M., Wilcox, M H, Allerberger, F, Vehreschild, M, Bouza, E., van Rossen, T M, Reigadas, E, van Prehn, J, Scharvik Olesen, B R, Norén, T., Allerberger, F., Ooijevaar, R.E., Scharvik Olesen, B.R., Burns, K, Ooijevaar, R E, van Prehn, J., Burns, K., Tschudin-Sutter, S., Krutova, M, Vogelzang, E.H., Hristea, A., Goorhuis, A., Fitzpatrick, F., Coia, J.E., Guery, B, Vehreschild, MJGT, Norén, T, Fitzpatrick, F, Krutova, M., Vogelzang, E H, Reigadas, E., Kuijper, E.J., Norén, Torbjorn, Wilcox, Mark H, Guery, Benoit, Olesen, Bente R. Scharvik,, Kuijper, Ed J.,, van Rossen, Tessel M, Vogelzang, Erik H.,, Burns, Karen, Burns, Karen,, Scharvik Olesen, Bente R, Norén, Torbjörn,, Goorhuis, Abraham,, Reigadas, Elena, Bouza, Emilio, van Prehn, Joffrey, Hristea, Adriana, Kuijper, Ed J, Guery, Benoit,, Goorhuis, Abraham, van Prehn, Joffrey,, Vehreschild, Maria J G T, Allerberger, Franz,, Tschudin-Sutter, Sarah, Ooijevaar, Rogier E, Reigadas, Elena,, Vehreschild, Maria J. G. T.,, van Rossen, Tessel M.,, Bouza, Emilio,, Coia, John E.,, Coia, John E, Allerberger, Franz, Fitzpatrick, Fidelma,, Wilcox, Mark H.,, Ooijevaar, Rogier E.,, Tschudin-Sutter, Sarah,, Vogelzang, Erik H, Fitzpatrick, Fidelma, Krutova, Marcela,, Krutova, Marcela, Hristea, Adriana,, Tessel M. van Rossen, Fidelma Fitzpatrick, Joffrey van Prehn, Ed J. Kuijper, Sarah Tschudin-Sutter, Erik H. Vogelzang, Torbjorn Norén, Benoit Guery, Adriana Hristea, Karen Burns, Franz Allerberger, Elena Reigadas, Emilio Bouza, Abraham Goorhuis, Marcela Krutova, Bente R. Scharvik Olesen, John E. Coia, Mark H. Wilcox, Maria J.G.T. Vehreschild, Rogier E. Ooijevaar   +99 more
core   +1 more source

Faecal microbiota transplantation for first and second episode of Clostridioides difficile infection

, 2023
Faecal microbiota transplantation is an accepted treatment for multiple recurrent Clostridioides difficile infections. 
Ed J Kuijper (9610556), Joffrey van Prehn (14673381), European Study Group for Clostridioides difficile (14691179), European Study Group for Host and Microbiota Interaction (14691180), Fidelma Fitzpatrick (7895483)   +4 more
core   +1 more source

In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden

Microbiology Spectrum, 2021
Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale, Chaitanya Tellapragada, Jelena Kornijenko, Carl Erik Nord, Christian G. Giske   +4 more
doaj   +1 more source

Diagnostic Methods of Clostridioides difficile Infection and Clostridioides difficile Ribotypes in Studied Sample [PDF]

Antibiotics, 2021
Background: Clostridioides (Clostridium) difficile is the most common nosocomial pathogen and antibiotic-related diarrhea in health-care facilities. Over the last few years, there was an increase in the incidence rate of C. difficile infection cases in Slovakia.
Elena Novakova, Zuzana Stofkova, Vladimira Sadlonova, Lukas Hleba   +3 more
openaire   +3 more sources

Outbreak of Clostridioides difficile infection in Silesian district hospital

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: In order to evaluate a Clostridioides difficile infection (CDI) outbreak between December 2018 and February 2019 in the internal medicine ward of a district hospital in Silesia, 6 stools from 5 patients were examined.
Klaudia T. Szarek, Monika A. Kabała, Krzysztof Sacha, Franciszek Drzymała, Adam Borek, Monika Pomorska-Wesołowska, Małgorzata Aptekorz, Gayane Martirosian   +7 more
doaj   +1 more source

Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa

Angewandte Chemie, EarlyView.
Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding, Sebastian R. Borgert, Wulf Blankenfeldt, Stephan A. Sieber   +3 more
wiley   +2 more sources

Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-Analysis

Antibiotics, 2019
Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,
Chia-Yu Chiu, Amara Sarwal, Addi Feinstein, Karen Hennessey   +3 more
doaj   +1 more source

Applications of Fecal Microbiota Transplantation: Emphasis on Clostridioides difficile Infections [PDF]

, 2021
Objective: This study aimed to perform a comprehensive review of clinical trials using fecal microbiota transplantation in cases of Clostridioides difficile infection.
Longo, Priscila Larcher, Montiel, José Maria, Oliveira, Rômulo Tadeu Dias de, Signorette, Juliana Peloso, Priscila Larcher Longo, Juliana Peloso Signorette, Rômulo Tadeu Dias de Oliveira, José Maria Montiel   +7 more
core   +1 more source

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +2 more sources

Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant

mBio, 2021
Antibiotic-associated colitis is often caused by infection with the bacterium Clostridioides difficileC ...
Jhansi L. Leslie, Matthew L. Jenior, Kimberly C. Vendrov, Alexandra K. Standke, Madeline R. Barron, Tricia J. O’Brien, Lavinia Unverdorben, Pariyamon Thaprawat, Ingrid L. Bergin, Patrick D. Schloss, Vincent B. Young   +10 more
doaj   +1 more source