Results 41 to 50 of about 54,164 (265)

Clostridioides (Clostridium) difficile Pacemaker Infection [PDF]

Open Forum Infectious Diseases, 2020
Abstract Clostridioides difficile is the leading cause of antibiotic-associated nosocomial diarrhea, but extra-intestinal manifestations are rare. We describe the first documented case of bacteraemia with pacemaker pocket and lead infection with the toxigenic C. difficile ribotype 014 with a lack of abdominal symptoms.
Anna Berkefeld, Fabian K Berger, Barbara C Gärtner, Nina Wantia, Anatol Prinzing, Karl-Ludwig Laugwitz, Dirk H Busch, Kathrin Rothe   +7 more
openaire   +3 more sources

Clostridioides Difficile Enteritis: Case Report and Literature Review

Antibiotics, 2022
Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis.
Artsiom Klimko, Cristian George Tieranu, Ana-Maria Curte, Carmen Monica Preda, Ioana Tieranu, Andrei Ovidiu Olteanu, Elena Mirela Ionescu   +6 more
doaj   +1 more source

Cost-Effectiveness Analysis of Bezlotoxumab Added to Standard of Care Versus Standard of Care Alone for the Prevention of Recurrent Clostridium difficile Infection in High-Risk Patients in Spain [PDF]

, 2018
Introduction Clostridium difficile infection (CDI) is the major cause of infectious nosocomial diarrhoea and is associated with considerable morbidity, mortality and economic impact.
Aceituno, Susana, Aragón, Belén, Cobo, Javier, Grau, Santiago, Jiang, Yiling, Maratia, Stefano, Pascual, Álvaro, Salavert, Miguel   +7 more
core   +3 more sources

Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection

JAMA Network Open, 2023
This phase 3, open-label, single-arm trial assesses the safety of SER-109 and the rate of recurrent Clostridioides difficile infection after administration of SER-109 following symptom resolution after antibiotic treatment among adults.
M. Sims, S. Khanna, P. Feuerstadt, T. Louie, C. Kelly, E. Huang, E. Hohmann, E. Wang, C. Oneto, Stuart H. Cohen, C. Berenson, Louis Korman, Christine Lee, B. Lashner, C. Kraft, M. Ramesh, M. Silverman, D. Pardi, A. de, A. Memişoğlu, David A. Lombardi, Brooke R. Hasson, B. McGovern, Lisa von Moltke   +23 more
semanticscholar   +1 more source

Enterotoxic Clostridia:Clostridioides difficileInfections [PDF]

Microbiology Spectrum, 2019
ABSTRACTClostridioides difficileis a Gram-positive, anaerobic, spore forming pathogen of both humans and animals and is the most common identifiable infectious agent of nosocomial antibiotic-associated diarrhea. Infection can occur following the ingestion and germination of spores, often concurrently with a disruption to the gastrointestinal microbiota,
S, Mileto, A, Das, D, Lyras
openaire   +2 more sources

Phage therapy for Clostridioides difficile infection

Frontiers in Immunology, 2022
Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is responsible for many healthcare-associated infections, such as nosocomial diarrhea following antibiotic treatment. Importantly, there have been cases of unsuccessful treatment and relapse related to the emergence of highly virulent strains of C.
Kosuke Fujimoto, Kosuke Fujimoto, Satoshi Uematsu, Satoshi Uematsu   +3 more
openaire   +3 more sources

Anaerobic 4-hydroxyproline utilization: Discovery of a new glycyl radical enzyme in the human gut microbiome uncovers a widespread microbial metabolic activity. [PDF]

, 2018
The discovery of enzymes responsible for previously unappreciated microbial metabolic pathways furthers our understanding of host-microbe and microbe-microbe interactions. We recently identified and characterized a new gut microbial glycyl radical enzyme
Balskus, Emily P, Huang, Yolanda Y, Martínez-Del Campo, Ana   +2 more
core   +1 more source

Fecal Microbiota Transplantation beyond Clostridioides Difficile Infection [PDF]

Clinical Endoscopy, 2021
With advancing analytical methods for gut microbes, many studies have been conducted, revealing that gut microbes cause various diseases, including gastrointestinal and non-gastrointestinal diseases. Accordingly, studies have been actively conducted to analyze the effects on the prevention and treatment of these diseases through changes in intestinal ...
Chang Mo Moon, Sung Noh Hong
openaire   +3 more sources

Environmental contamination with clostridioides (Clostridium) difficile in Vietnam [PDF]

, 2023
AIMS: To investigate the prevalence, molecular type, and antimicrobial susceptibility of Clostridioides difficile in the environment in Vietnam, where little is known about C. difficile.
Bui, Huong T. T., Bui, Nguyen T., Collins, Deirdre A., Khun, Peng A., Phi, Long D., Riley, Thomas V., Trinh, Luong D., Vu, Quyen T. H.   +7 more
core   +2 more sources

In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden

Microbiology Spectrum, 2021
Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale, Chaitanya Tellapragada, Jelena Kornijenko, Carl Erik Nord, Christian G. Giske   +4 more
doaj   +1 more source