Results 41 to 50 of about 1,730,491 (239)

In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden

Microbiology Spectrum, 2021
Clostridioides difficile infection represents a growing clinical challenge. The new compound omadacycline is a potential treatment alternative, as many antibiotics have limited activity or are rarely used due to costs and side effects.
Angela Camporeale, Chaitanya Tellapragada, Jelena Kornijenko, Carl Erik Nord, Christian G. Giske   +4 more
doaj   +1 more source

Managing Clostridium difficile infection in hospitalised patients [PDF]

, 2014
Checklists are not a new phenomenon and have been used in the aviation industry for some time as a means of ensuring safety and minimising harm. Checklists are now used commonly in health care to improve patient safety.
Topping, Annie, Denton, Andrea, Denton, A, Topping, A; id_orcid, Humphreys, Paul, Humphreys, P   +5 more
core   +1 more source

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. [PDF]

, 2012
Relapsing C. difficile disease in humans is linked to a pathological imbalance within the intestinal microbiota, termed dysbiosis, which remains poorly understood. We show that mice infected with epidemic C.
Parkhill Julian, Duncan Sylvia H., Deakin, Laura J., Thomas R. Connor (125272), Schreiber Fernanda, Brandt, Cordelia, Pickard Derek J., Flint, Harry J, Harry J. Flint (125298), Parkhill, J, Flint, Harry James, Trevor D. Lawley (125265), Simon Clare, Roland Rad (125284), David Goulding (125280), Julian Parkhill (30393), Claire Raisen (125275), Schreiber, F, Clare Simon, Taane G Clark, Deakin Laura J., Connor Thomas R., Taane G. Clark (106263), Clark, Taane G., Gordon Dougan, Duncan, SH, Sylvia H. Duncan (125296), Stares, Mark D., Raisen Claire, Roland Rad, Trevor D Lawley, Rad, Roland, Derek J. Pickard (125293), Sylvia H Duncan, Walker Alan W., Harry J Flint, Goulding David, Rad, R, Derek J Pickard, Deakin, LJ, Schreiber, Fernanda, Clark, Taane G, Clark, TG, Rad Roland, Walker, Alan W, Flint Harry J., Goulding, David, Alan W. Walker (50247), Raisen, C, Stares, MD, Pickard, Derek J, Flint, Harry J., Lawley, Trevor D, Deakin, Laura J, Connor, Thomas R, Claire Raisen, Brandt, C, Walker, AW, Mark D Stares, Walker, Alan W., Duncan, Sylvia H, Dougan Gordon, Connor, Thomas Richard, Clare, Simon, Pickard, Derek J., Laura J Deakin, Fernanda Schreiber, Fernanda Schreiber (85280), Lawley, TD, Clare, S, Julian Parkhill, Alan W Walker, David Goulding, Lawley, Trevor D., Raisen, Claire, Mark D. Stares (125271), Cordelia Brandt (125287), Laura J. Deakin (125290), Brandt Cordelia, Dougan, Gordon, Pickard, DJ, Duncan, Sylvia H., Parkhill, Julian, Simon Clare (125268), Clark Taane G., Flint, HJ, Gordon Dougan (30395), Thomas R Connor, Stares Mark D., Stares, Mark D, Goulding, D, Cordelia Brandt, Connor, TR, Dougan, G, Lawley Trevor D.   +94 more
core   +1 more source

Outbreak of Clostridioides difficile infection in Silesian district hospital

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: In order to evaluate a Clostridioides difficile infection (CDI) outbreak between December 2018 and February 2019 in the internal medicine ward of a district hospital in Silesia, 6 stools from 5 patients were examined.
Klaudia T. Szarek, Monika A. Kabała, Krzysztof Sacha, Franciszek Drzymała, Adam Borek, Monika Pomorska-Wesołowska, Małgorzata Aptekorz, Gayane Martirosian   +7 more
doaj   +1 more source

Diagnostic Methods of Clostridioides difficile Infection and Clostridioides difficile Ribotypes in Studied Sample [PDF]

Antibiotics, 2021
Background: Clostridioides (Clostridium) difficile is the most common nosocomial pathogen and antibiotic-related diarrhea in health-care facilities. Over the last few years, there was an increase in the incidence rate of C. difficile infection cases in Slovakia.
Elena Novakova, Zuzana Stofkova, Vladimira Sadlonova, Lukas Hleba   +3 more
openaire   +3 more sources

Trends in U.S. Burden of Clostridioides difficile Infection and Outcomes

, 2020
Emerging Infections Program Clostridioides difficile Infection Working Group: Lauren Korhonen, Brittany Martin, Geoffrey Brousseau, Wendy Bamberg, Elizabeth Basiliere, James Meek, Rebecca Perlmutter, Maria Bye, Tory Whitten, Emily B.
Beldavs, Zintars G., Kainer, Marion A., Dumyati, Ghinwa K., Phipps, Erin C., Mu, Yi, McDonald, L. Clifford, Karlsson, Maria, Holzbauer, Stacy M., Winston, Lisa G., Johnston, Helen, Olson, Danyel, Wilson, Lucy E., Gerding, Dale N., Guh, Alice Y., Farley, Monica M., Emerging Infections Program Clostridioides difficile Infection Working Group   +15 more
core   +1 more source

Biochemical characterization of sporulation-related histidine kinases in Clostridioides difficile [PDF]

, 2022
Histidine kinases are one of the two proteins that constitute a two-component signal transduction system. These systems are used by bacteria, fungi, and several plants to sense the conditions of their environment and alter their behavior to ensure ...
Shukla, Kriti
core  

Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-Analysis

Antibiotics, 2019
Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,
Chia-Yu Chiu, Amara Sarwal, Addi Feinstein, Karen Hennessey   +3 more
doaj   +1 more source

Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant

mBio, 2021
Antibiotic-associated colitis is often caused by infection with the bacterium Clostridioides difficileC ...
Jhansi L. Leslie, Matthew L. Jenior, Kimberly C. Vendrov, Alexandra K. Standke, Madeline R. Barron, Tricia J. O’Brien, Lavinia Unverdorben, Pariyamon Thaprawat, Ingrid L. Bergin, Patrick D. Schloss, Vincent B. Young   +10 more
doaj   +1 more source

Freeze-dried fecal samples are biologically active after long-lasting storage and suited to fecal microbiota transplantation in a preclinical murine model of Clostridioides difficile infection

Gut Microbes, 2020
Fecal microbiota transplantation is now recommended for treating recurrent forms of Clostridioides difficile infection. Recent studies have reported protocols using capsules of either frozen or freeze-dried stool allowing oral administration in in- and ...
Julie Reygner, Christine Charrueau, Johanne Delannoy, Camille Mayeur, Véronique Robert, Céline Cuinat, Thierry Meylheuc, Aurélie Mauras, Jérémy Augustin, Ioannis Nicolis, Morgane Modoux, Francisca Joly, Anne-Judith Waligora-Dupriet, Muriel Thomas, Nathalie Kapel   +14 more
doaj   +1 more source