Results 31 to 40 of about 1,730,491 (239)

ANTIDEPRESSANT MEDICATIONS ARE ASSOCIATED WITH INCREASED RISK OF HOSPITAL-ACQUIRED CLOSTRIDIOIDES DIFFICILE INFECTION: A POPULATION-BASED STUDY [PDF]

open access: yesArquivos de Gastroenterologia, 2023
Background: During the past decade, Clostridioides difficile infection (CDI) has become the most common cause of antibiotic-associated diarrhea. Several risk factors have been implicated.
Antoine BOUSTANY   +4 more
doaj   +1 more source

Opportunities for Nanomedicine in Clostridioides difficile Infection [PDF]

open access: yesAntibiotics, 2021
Clostridioides difficile, a spore-forming bacterium, is a nosocomial infectious pathogen which can be found in animals as well. Although various antibiotics and disinfectants were developed, C. difficile infection (CDI) remains a serious health problem. C.
Pei-Wen Wang   +3 more
openaire   +3 more sources

Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults

open access: yesSAGE Open Medicine, 2020
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12 
Kathryn A Connor, Kelly M Conn
doaj   +1 more source

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

open access: yesNature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh   +7 more
doaj   +1 more source

An Integrated Pipeline For Prediction of Clostridioides Difficile Infection [PDF]

open access: yesScientific Reports, 2022
Abstract With the expansion of electronic health records(EHR)-linked genomic data comes the development of machine learning-enable models. There is a pressing need to develop robust pipelines to evaluate performance of integrated models and minimize systemic bias. We developed a prediction model of symptomatic Clostridioides difficile infection(
Jiang Li   +8 more
openaire   +3 more sources

Phage therapy for Clostridioides difficile infection

open access: yesFrontiers in Immunology, 2022
Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is responsible for many healthcare-associated infections, such as nosocomial diarrhea following antibiotic treatment. Importantly, there have been cases of unsuccessful treatment and relapse related to the emergence of highly virulent strains of C.
Kosuke Fujimoto   +3 more
openaire   +3 more sources

Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

open access: yesInfectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich   +15 more
doaj   +1 more source

Impact of COVID-19 pandemic on prevalence of Clostridioides difficile infection in a UK tertiary centre [PDF]

open access: yes, 2022
Serious concerns have been raised about a possible increase in cases of Clostridioides difficile infection (CDI) during the COVID-19 pandemic. We conducted a retrospective observational single centre study which revealed that total combined community and
Hills, Tim   +8 more
core   +1 more source

Rare Clinical Association between Clostridioides difficile Infection and Ischemic Colitis: Case Report and Literature Review

open access: yesMedicina, 2021
Background and Objectives: Gut microbiota plays an important role in the wellbeing of the host through different interactions between microflora constituents. In certain instances, Clostridioides difficile may pullulate, causing infection with associated
Elena Mirela Ionescu   +6 more
doaj   +1 more source

Clostridioides Difficile Enteritis: Case Report and Literature Review

open access: yesAntibiotics, 2022
Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis.
Artsiom Klimko   +6 more
doaj   +1 more source

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