Results 31 to 40 of about 1,849,474 (227)

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

open access: yesNature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh   +7 more
doaj   +1 more source

An Integrated Pipeline For Prediction of Clostridioides Difficile Infection [PDF]

open access: yesScientific Reports, 2022
Abstract With the expansion of electronic health records(EHR)-linked genomic data comes the development of machine learning-enable models. There is a pressing need to develop robust pipelines to evaluate performance of integrated models and minimize systemic bias. We developed a prediction model of symptomatic Clostridioides difficile infection(
Jiang Li   +8 more
openaire   +3 more sources

Clostridioides (Clostridium) difficile infection: Review of literature

open access: yes, 2022
Clostridioides (Clostridium) difficile (C. difficile) is a gram-positive bacterium that infects the large intestine. The number of clostridium difficile infections has increased in the recent years due to multiple risk factors including frequent use of ...
Varun Sodhi   +6 more
core   +1 more source

Possible contribution of shoes to clostridioides difficile transmission within hospitals [PDF]

open access: yes, 2020
Clostridioides difficile remains the most common cause of healthcare-associated intestinal infection. Hospitalized patients aged >65 years and receiving antibiotic therapy are the population most at risk of C. difficile infection (CDI)
Blazevic, Ines   +11 more
core   +1 more source

Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

open access: yesInfectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich   +15 more
doaj   +1 more source

Microbiome Therapeutics for Clostridioides difficile Infection. [PDF]

open access: yesInfect Dis Clin North Am
Microbiota-based therapies are used increasingly for the treatment and prevention of Clostridioides difficile infection (CDI), particularly in cases of recurrent CDI (rCDI). This review discusses the different types of microbiota-based therapies, including fecal microbiota transplant, fecal microbiota products, and live biotherapeutic products.
Lucky CW   +4 more
europepmc   +3 more sources

Rare Clinical Association between Clostridioides difficile Infection and Ischemic Colitis: Case Report and Literature Review

open access: yesMedicina, 2021
Background and Objectives: Gut microbiota plays an important role in the wellbeing of the host through different interactions between microflora constituents. In certain instances, Clostridioides difficile may pullulate, causing infection with associated
Elena Mirela Ionescu   +6 more
doaj   +1 more source

Economic burden attributable to Clostridioides difficile infections in South Korea: a nationwide propensity score-matched study

open access: yes, 2022
Background: Clostridioides (Clostridium) difficile is an important pathogen that causes diarrhoea in patients who take antibacterial drugs. Considering the limited medical resources, it is necessary to prioritize the management of threats caused by ...
박윤수, Y.S. Park, Y.A. Kim, K.J. Son
core   +1 more source

Clostridioides Difficile Enteritis: Case Report and Literature Review

open access: yesAntibiotics, 2022
Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis.
Artsiom Klimko   +6 more
doaj   +1 more source

Changes in the Epidemiology of Clostridioides difficile Infection. [PDF]

open access: yesInfect Dis Clin North Am
This article describes the epidemiology of Clostridioides difficile infection (CDI) by outlining common approaches to CDI surveillance, including the application of a case definition and risk adjustment, and summarizing recent global trends in the incidence or prevalence of CDI.
Guh AY, McDonald LC.
europepmc   +4 more sources

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