Results 51 to 60 of about 1,730,491 (239)

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases

International Journal of Infectious Diseases, 2021
Clostridioides difficile infection is an increasing presence worldwide. Prevention is multipronged, reflecting a complex and evolving epidemiology. Multiple guidelines exist regarding the prevention of C.
Michelle Doll, Alexandre R. Marra, Anucha Apisarnthanarak, Amal Saif Al-Maani, Salma Abbas, Victor D. Rosenthal   +5 more
doaj   +1 more source

Role of diagnostic stewardship in reducing healthcare-facility–onset Clostridioides difficile infections

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
We describe the implementation of an electronic medical record “hard stop” to decrease inappropriate Clostridioides difficile testing across a 5-hospital health system, effectively reducing the rates of healthcare-facility–onset C.
Anita B. Shallal, Medha Cherabuddi, Lance Podsiad, Christopher Gortat, Clare Shanahan, Tarlisha Holsey, Linoj Samuel, George Alangaden, Geehan Suleyman   +8 more
doaj   +1 more source

Management of Clostridioides difficile Infection [PDF]

Critical Care Nurse, 2019
Clostridioides (formerly Clostridium) difficile infection is among the most identified causes of health care-associated infections in US hospitals and remains a major public health problem. The incidence and severity of C difficile infection are high among critically ill patients.
Christina, Clarkin, Stephanie, Quist, Renata, Shamis, Amber E, King, Bhavik M, Shah   +4 more
openaire   +2 more sources

The Bacterial Gut Microbiota of Adult Patients Infected, Colonized or Noncolonized by Clostridioides difficile

Microorganisms, 2020
Gut microbiota composition in patients with Clostridioides difficile colonization is not well investigated. We aimed to identify bacterial signatures associated with resistance and susceptibility to C.
Monique J. T. Crobach, Quinten R. Ducarmon, Elisabeth M. Terveer, Celine Harmanus, Ingrid M. J. G. Sanders, Kees M. Verduin, Ed J. Kuijper, Romy D. Zwittink   +7 more
doaj   +1 more source

Clostridioides difficile infection: an update

Infezioni in Medicina
Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment cost and increased hospitalisation time.
Federica, Salvati, Francesca, Catania, Rita, Murri, Massimo, Fantoni, Carlo, Torti   +4 more
openaire   +2 more sources

Clostridioides difficile co-infection with Enterohemorrhagic Escherichia coli (EHEC)—a potentially fatal combination

IDCases, 2020
There has been a significant increase in hospital and community acquired Clostridioides difficile infection in the past decade. In addition to CDI, the rate of infection with enterohemorrhagic Escherichia coli (EHEC) has also increased by 28% in United ...
Farah Deshmukh, Upasana Agrawal, Nancy Merrell   +2 more
doaj   +1 more source

Reduction in Health Care Facility–Onset Clostridioides difficile Infection: A Quality Improvement Initiative

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2021
Objective: To reduce health care facility–onset (HCFO) Clostridioides difficile infection (CDI) incidence by improving diagnostic stewardship and reducing the inappropriate testing of C difficile assays.
Himesh B. Zaver, MD, Varun P. Moktan, MD, Eugene P. Harper, MD, Aman Bali, MD, Ayan Nasir, MD, Carla Foulks, MD, Justin Kuhlman, MD, Max Green, MD, Gillian A. Algan, BS, Heather C. Parth, MPH, Melody Wu-Ballis, BS, Sandra DiCicco, BS, Brenda T. Smith, BS, Ronald N. Owen, BS, Lorraine S. Mai, BS, Sarah L. Spiros, BS, John Griffis, BS, Daphne T. Ramsey Walker, BS, D. Jane Hata, PhD, Justin M. Oring, DO, Harry R. Powers, MD, Wendelyn Bosch, MD   +21 more
doaj   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

Advanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena, Soyeon Lee, Youngeun Choi, Jonathan L'Heureux‐Hache, Jiaying Liu, Sadman Sakib, Sara M. Imani, Marek Smieja, Yingfu Li, Todd Hoare, Leyla Soleymani   +10 more
wiley   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

The analysis of the epidemic status and risk factors associated with different genotypes Clostridioides difficile mixed infection

BMC Microbiology
Background Clostridioides difficile is the main pathogen of antibiotic-associated diarrhea and pseudomembranous enteritis. Mixed Clostridioides difficile infection are simultaneous infection of the same host with strains of different genotypes. In recent
Yulian Zhang, Jing Yang, Honglian Wei, Jie Wang, Pu Qin, Qianqing Li, Cuixin Qiang, Jianhong Zhao   +7 more
doaj   +1 more source