Results 51 to 60 of about 54,164 (265)

High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection [PDF]

, 2017
Objectives: Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare.
Acharya, K. Ravi, Hamed, Mohamed R., Humphreys, D.P., MacKenzie, B., Monaghan, Tanya M., Negm, Ola H., Shone, Clifford C., Wilcox, Mark H.   +7 more
core   +2 more sources

SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial

Clinical Infectious Diseases, 2020
Background Recurrent Clostridioides difficile infection (rCDI) is associated with loss of microbial diversity and microbe-derived secondary bile acids, which inhibit C. difficile germination and growth.
B. McGovern, Christopher B. Ford, M. Henn, D. Pardi, S. Khanna, E. Hohmann, E. O’Brien, C. Desjardins, P. Bernardo, J. Wortman, M. Lombardo, Kevin D. Litcofsky, J. Winkler, Christopher McChalicher, Sunny S Li, Amelia Tomlinson, Madhumitha Nandakumar, D. N. Cook, R. Pomerantz, J. Auniņš, M. Trucksis   +20 more
semanticscholar   +1 more source

Clostridioides difficile Infection

RGUHS Journal of Medical Sciences, 2022
In the past decade Clostrdioides difficile has become a leading enteric pathogen causing antibiotic-associated diarrohoea and colitis. The manifestations range from diarrhoea to life-threatening damage to the large intestine. It is noted as a nosocomial and community acquired infection in most of the countries including India.
openaire   +1 more source

Response: Commentary: Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors [PDF]

, 1998
Official Student Newspaper Issue is 20 pages ...
Hall, Lindsay J., Kiu, Raymond
core   +20 more sources

Phages and human health: More than idle hitchhikers [PDF]

, 2019
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T, Handley, Scott A, Lawrence, Dylan   +2 more
core   +2 more sources

Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant

mBio, 2021
Antibiotic-associated colitis is often caused by infection with the bacterium Clostridioides difficileC ...
Jhansi L. Leslie, Matthew L. Jenior, Kimberly C. Vendrov, Alexandra K. Standke, Madeline R. Barron, Tricia J. O’Brien, Lavinia Unverdorben, Pariyamon Thaprawat, Ingrid L. Bergin, Patrick D. Schloss, Vincent B. Young   +10 more
doaj   +1 more source

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting [PDF]

, 2019
Penicillin allergies are among of the most commonly reported allergies, yet only 10% of these patients are truly allergic. This leads to potential inadvertent negative consequences for patients and makes treatment decisions challenging for clinicians ...
Avery, Lisa M., Bookstaver, P. Brandon, Justo, Julie Ann, Kufel, Wesley D.   +3 more
core   +3 more sources

Outbreak of Clostridioides difficile infection in Silesian district hospital

Annales Academiae Medicae Silesiensis, 2023
INTRODUCTION: In order to evaluate a Clostridioides difficile infection (CDI) outbreak between December 2018 and February 2019 in the internal medicine ward of a district hospital in Silesia, 6 stools from 5 patients were examined.
Klaudia T. Szarek, Monika A. Kabała, Krzysztof Sacha, Franciszek Drzymała, Adam Borek, Monika Pomorska-Wesołowska, Małgorzata Aptekorz, Gayane Martirosian   +7 more
doaj   +1 more source

Durable reduction of Clostridioides difficile infection recurrence and microbiome restoration after treatment with RBX2660: results from an open-label phase 2 clinical trial

BMC Infectious Diseases, 2022
Background Effective treatment options for recurrent Clostridioides difficile infection (rCDI) are limited, with high recurrence rates associated with the current standard of care. Herein we report results from an open-label Phase 2 trial to evaluate the
R. Orenstein, E. Dubberke, S. Khanna, Christine H. Lee, David L. Yoho, Stuart Johnson, G. Hecht, H. Dupont, D. Gerding, Ken F Blount, S. Mische, Adam J Harvey   +11 more
semanticscholar   +1 more source

Management of Clostridioides difficile Infection [PDF]

Critical Care Nurse, 2019
Clostridioides (formerly Clostridium) difficile infection is among the most identified causes of health care-associated infections in US hospitals and remains a major public health problem. The incidence and severity of C difficile infection are high among critically ill patients.
Christina, Clarkin, Stephanie, Quist, Renata, Shamis, Amber E, King, Bhavik M, Shah   +4 more
openaire   +2 more sources