Results 51 to 60 of about 1,849,474 (227)

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases

International Journal of Infectious Diseases, 2021
Clostridioides difficile infection is an increasing presence worldwide. Prevention is multipronged, reflecting a complex and evolving epidemiology. Multiple guidelines exist regarding the prevention of C.
Michelle Doll, Alexandre R. Marra, Anucha Apisarnthanarak, Amal Saif Al-Maani, Salma Abbas, Victor D. Rosenthal   +5 more
doaj   +1 more source

Management of Clostridioides difficile Infection [PDF]

Critical Care Nurse, 2019
Clostridioides (formerly Clostridium) difficile infection is among the most identified causes of health care-associated infections in US hospitals and remains a major public health problem. The incidence and severity of C difficile infection are high among critically ill patients.
Christina, Clarkin, Stephanie, Quist, Renata, Shamis, Amber E, King, Bhavik M, Shah   +4 more
openaire   +2 more sources

Freeze-dried fecal samples are biologically active after long-lasting storage and suited to fecal microbiota transplantation in a preclinical murine model of Clostridioides difficile infection

Gut Microbes, 2020
Fecal microbiota transplantation is now recommended for treating recurrent forms of Clostridioides difficile infection. Recent studies have reported protocols using capsules of either frozen or freeze-dried stool allowing oral administration in in- and ...
Julie Reygner, Christine Charrueau, Johanne Delannoy, Camille Mayeur, Véronique Robert, Céline Cuinat, Thierry Meylheuc, Aurélie Mauras, Jérémy Augustin, Ioannis Nicolis, Morgane Modoux, Francisca Joly, Anne-Judith Waligora-Dupriet, Muriel Thomas, Nathalie Kapel   +14 more
doaj   +1 more source

Role of diagnostic stewardship in reducing healthcare-facility–onset Clostridioides difficile infections

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
We describe the implementation of an electronic medical record “hard stop” to decrease inappropriate Clostridioides difficile testing across a 5-hospital health system, effectively reducing the rates of healthcare-facility–onset C.
Anita B. Shallal, Medha Cherabuddi, Lance Podsiad, Christopher Gortat, Clare Shanahan, Tarlisha Holsey, Linoj Samuel, George Alangaden, Geehan Suleyman   +8 more
doaj   +1 more source

Clostridioides difficile infection: an update

Infezioni in Medicina
Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming anaerobic bacterium emerged as a leading cause of diarrhea globally. CDI's (Clostridioides difficile infection) impact on healthcare systems is concerning due to high treatment cost and increased hospitalisation time.
Federica, Salvati, Francesca, Catania, Rita, Murri, Massimo, Fantoni, Carlo, Torti   +4 more
openaire   +2 more sources

Clostridioides difficile infection: a comprehensive review for primary providers

, 2021
Clostridioides difficile infection (CDI) is an issue of great concern due to its rising incidence, recurrence, morbidity and impact on healthcare spending.
Harris Dana M., Stancampiano Fernando, Cortés Pedro, Bi Yan, Cooper Jane H., Valery Jose R., Jose R. Valery, Jane H. Cooper, Pedro Cortés, Dana M. Harris, Yan Bi, Fernando Stancampiano   +11 more
core   +1 more source

Knowledge and experiences of nurses/technicians about Clostridioides difficile infection

, 2023
Ovaj završni rad istražuje znanja i iskustva medicinskih sestara/tehničara o infekciji Clostridioides difficile. Clostridioides difficile infekcija predstavlja izazov za zdravstveni sustav i zahtijeva pažljivo upravljanje radi prevencije širenja ...
Rendulić, Barbara
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection [PDF]

, 2021
Clostridioides difficile spores produced during infection are important for the recurrence of the disease. Here, we show that C. difficile spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin-α5β1 and vitronectin-αvβ1 ...
Cofré Araneda, Glenda, Orozco Aguilar, Josué, Reyes Ramírez, Rodrigo, Brito Silva, Christian, Castro Córdova, Pablo, Mendoza-León, M.J., Minton, N.P., Kuehne, S.A., Brito-Silva, C., Pizarro-Guajardo, M., Reyes-Ramírez, R., Cofré-Araneda, Glenda, Cofré-Araneda, G., Mendoza-León, María José, Castro-Córdova, P., Pizarro Guajardo, Marjorie, Paredes-Sabja, Daniel, Orozco-Aguilar, J., Mendoza León, María José, Paredes-Sabja, D., Orozco-Aguilar, Josué, Brito-Silva, Christian, Mora Uribe, Paola, Kuehne, Sarah Anna, Mora-Uribe, Paola, Minton, Nigel P., Castro-Córdova, Pablo, Kuehne, Sarah A., Reyes-Ramírez, Rodrigo, Pizarro-guajardo, Marjorie, Paredes Sabja, Daniel, Mora-Uribe, P., Minton, Nigel Peter, Paola Mora-Uribe, Glenda Cofré-Araneda, Sarah A. Kuehne, Christian Brito-Silva, Daniel Paredes-Sabja, Pablo Castro-Córdova, María José Mendoza-León, Nigel P. Minton, Rodrigo Reyes-Ramírez, Josué Orozco-Aguilar, Marjorie Pizarro-Guajardo   +43 more
core   +1 more source