Results 71 to 80 of about 1,730,491 (239)

Extraintestinal Clostridioides difficile Infection (CDI): A Recurrent Battle with Resilient Abdominal Wall Abscess

European Journal of Case Reports in Internal Medicine, 2023
Clostridioides (formerly Clostridium) difficile infection is a common and costly healthcare-associated infection. Extraintestinal C. difficile infection is rarely encountered, especially in isolation.
Justine Chinnappan, Murtaza Hussain, Dominic Awuah, Ekwevugbe Ogbon, Ghassan Bachuwa, Philip McDonald   +5 more
doaj   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Fecal microbiota transplantation in a patient hospitalized in the intensive care unit – Case report

Heliyon
Clostridioides difficile infections are difficult and serious problem occurring in patients staying in intensive care units. In recent years, the number and severity of these infections, as well as the mortality rate, have been increasing, posing a ...
Katarzyna Oliwa-Libumska, Aleksandra Jaworska-Czerwinska, Malgorzata Mallek-Grabowska, Robert Wlodarski, Przemyslaw Zuratynski, Bartosz Kozlowski   +5 more
doaj   +1 more source

National trends in pathogen‐specific diagnoses and outcomes among hospitalizations for infectious diarrhea

Journal of Hospital Medicine, EarlyView.
Abstract Background The diagnostic evaluation of infectious diarrhea has evolved with increasing adoption of multiplex gastrointestinal nucleic acid amplification tests and changing diagnostic strategies for Clostridioides difficile. Objectives We aimed to assess changes in inpatient pathogen‐specific documentation rates and clinical outcomes on a ...
David Wong Arias, Spencer R. Goble, Mauricio Torrealba   +2 more
wiley   +1 more source

The cytotoxic synergy between Clostridioides difficile toxin B and proinflammatory cytokines: an unholy alliance favoring the onset of Clostridioides difficile infection and relapses

MicrobiologyOpen, 2020
Clostridioides difficile infection (CDI) represents an important health problem worldwide, with significant morbidity and mortality. This infection has also high recurrence rates, whose pathophysiological grounds are still poorly understood. Based on our
Gabrio Bassotti, Andrea Marchegiani, Pierfrancesco Marconi, Katia Fettucciari   +3 more
doaj   +1 more source

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

Gut Pathogens, 2021
Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C.
Seung Woo Ahn, Se Hee Lee, Uh Jin Kim, Hee-Chang Jang, Hak-Jong Choi, Hyon E. Choy, Seung Ji Kang, Seong Woon Roh   +7 more
doaj   +1 more source

Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric acute pancreatitis (AP), Crohn's disease (CD), and irritable bowel syndrome (IBS) are associated with gut dysbiosis, but differences and similarities between conditions are unknown. We hypothesized that gut microbial ecology would differ across these disorders. Methods Stool was collected from 120 subjects (AP [n = 30], CD
Neha R. Santucci, Chinenye R. Dike, Jenny Hellmann, Nicholas J. Ollberding, Qing Duan, Philip Minar, Lee A. Denson, David B. Haslam, Daniel Castillo, Maisam Abu‐El‐Haija   +9 more
wiley   +1 more source

Clostridioides difficile infections: Preventive strategies [PDF]

, 2023
Clostridioides difficile infections primarily affect elderly, hospitalised patients treated with antibiotics and are among the most common healthcare-related infections. This thesis aimed to improve the understanding of the best prevention strategies for
Edman Wallér, Jon
core   +1 more source

Incidence of hospital-acquired toxin-producing clostridioides difficile infection between the pre-pandemic (2017–2019) and pandemic (2020–2022): a retrospective cohort study

Archives of Public Health
Background In 2020, the World Health Organization declared SARS-CoV-2 a global public health emergency. Healthcare systems were forced to reorganize care delivery and implement wide-ranging infection control strategies. Among hospital-acquired infections,
Raquel García Rodríguez, María José Pereira Rodríguez, Alejandra Pilar García López, Fabián Freijedo Fariñas, Angela Nogueira Gómez   +4 more
doaj   +1 more source

Pediatric Clostridiodes difficile infection with toxic megacolon successfully treated with fecal microbiota transplantation

JPGN Reports, EarlyView.
Abstract The rising incidence of pediatric Clostridioides difficile infection (CDI), particularly in medically complex patients, calls for novel, individualized treatments. While fecal microbiota transplantation (FMT) is well‐described for recurrent CDI, this report describes the first pediatric case of fulminant CDI with toxic megacolon successfully ...
Dana McCarney, Pamela Chen, Jenna Simes, Stacy A. Kahn   +3 more
wiley   +1 more source