Results 91 to 100 of about 1,849,474 (227)

sj-docx-1-tag-10.1177_17562848211050443 – Supplemental material for Kinetics of polymerase chain reaction positivity in patients with Clostridioides difficile infection

open access: yes, 2021
Supplemental material, sj-docx-1-tag-10.1177_17562848211050443 for Kinetics of polymerase chain reaction positivity in patients with Clostridioides difficile infection by Srishti Saha, Devvrat Yadav, Ryan Pardi, Robin Patel, Sahil Khanna and Darrell ...
Ryan Pardi (11540668)   +5 more
core   +1 more source

Competitive SELEX Strategy for High‐Affinity Aptamer Isolation and Enhanced Biosensing

open access: yesSmall, EarlyView.
A novel competitive SELEX strategy was developed to isolate high‐affinity aptamers by using a lower‐affinity competitor during the selection process. This approach enabled the identification of an aptamer with exceptional binding affinity, significantly improving target detection sensitivity.
Jiuxing Li   +4 more
wiley   +1 more source

Mechanisms of Clostridioides difficile glucosyltransferase toxins and their roles in pathology: insights and emerging therapeutic strategies

open access: yesFrontiers in Cellular and Infection Microbiology
Clostridioides difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis, manifesting as mild diarrhea, fulminant colitis, and even death.
Xin Wen   +6 more
doaj   +1 more source

Microbiome Insights Into Zoonotic Risk at Wildlife–Human Interfaces in a Transitioning Landscape in Thailand

open access: yesIntegrative Zoology, EarlyView.
This study shows how ecological transitions, such as reforestation in Southeast Asia, reshape host–microbe–pathogen dynamics at the wildlife–domestic interface. By integrating long‐read microbiome sequencing, ecological gradients, and statistical and network analysis, we identify host species that disproportionately contribute to pathogen diversity and
Pauline Van Leeuwen   +9 more
wiley   +1 more source

N Engl J Med [PDF]

open access: yes
BACKGROUNDEfforts to prevent Clostridioides difficile infection continue to expand across the health care spectrum in the United States. Whether these efforts are reducing the national burden of C.

core  

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes   +2 more
wiley   +1 more source

Risk factors for further recurrences of Clostridioides difficile infection at the first and second recurrence: a retrospective cohort

open access: yesBMC Infectious Diseases
Background Recurrent Clostridioides difficile infection is most effectively treated with faecal microbiota transplantation. Swedish and European guidelines suggest faecal microbiota transplantation after a first or second recurrence, respectively.
Måns Stefansson   +5 more
doaj   +1 more source

Medication Use and Risk of Microscopic Colitis: A Propensity‐Matched Analysis of US Adults ≥ 50 Years (2014–2024)

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Commonly prescribed NSAIDs, PPIs and SSRIs were associated with a higher risk of microscopic colitis after propensity score matching, whereas ACE inhibitors, ARBs and statins showed no significant association. ABSTRACT Background The association between medications—including non‐steroidal anti‐inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs ...
Yassine Kilani   +6 more
wiley   +1 more source

Clostridioides difficile Enteritis Induced Anastomotic Rupture: A Case Report and Literature Review

open access: yesCase Reports in Surgery, 2020
Background. A 76-year-old male patient who suffered small bowel anastomotic dehiscence believed to be a complication provoked by Clostridioides difficile enteritis. Case Presentation. The patient was a 76-year-old male who underwent small bowel resection
David R. Velez, Mentor Ahmeti
doaj   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

open access: yesBritish Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy