Results 101 to 110 of about 54,164 (265)

A Systematic Literature Review on Risk Factors for and Timing of Clostridioides difficile Infection in the United States

Infectious Disease and Therapy
Clostridioides difficile infection (CDI) is a major public health threat. Up to 40% of patients with CDI experience recurrent CDI (rCDI), which is associated with increased morbidity.
Jennifer Eeuwijk, Guilherme S Ferreira, J. Yarzábal, Mirna Robert-Du Ry van Beest Holle   +3 more
semanticscholar   +1 more source

Emerging Options for the Prevention and Management of Clostridioides difficile Infection

Drugs, 2023
Agents in development for the prevention or treatment of Clostridioides difficile infection can be split into three broad categories: antibiotics, microbiome restoration, and vaccines.
A. Gonzales-Luna, T. Carlson, K. Garey
semanticscholar   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

iMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li, Ying Chen, Xi Chen, Weili Lu, Jie Liao, Jiaqi Wang, Qiwei Liu, Yanzi Chang, Zeping Xu, Yanye Tu, Yang Zhou, Jing Xue, Binbin Wang, Kang Chen, Keyun Cheng, Chunlai Zeng, Hong Li, Qing Shen   +17 more
wiley   +1 more source

Extraintestinal Clostridioides difficile Infection (CDI): A Recurrent Battle with Resilient Abdominal Wall Abscess

European Journal of Case Reports in Internal Medicine, 2023
Clostridioides (formerly Clostridium) difficile infection is a common and costly healthcare-associated infection. Extraintestinal C. difficile infection is rarely encountered, especially in isolation.
Justine Chinnappan, Murtaza Hussain, Dominic Awuah, Ekwevugbe Ogbon, Ghassan Bachuwa, Philip McDonald   +5 more
doaj   +1 more source

The role of the gut microbiome in colonization resistance and recurrent Clostridioides difficile infection

Therapeutic Advances in Gastroenterology, 2022
The species composition of the human gut microbiota is related to overall health, and a healthy gut microbiome is crucial in maintaining colonization resistance against pathogens.
Anna M. Seekatz, N. Safdar, S. Khanna
semanticscholar   +1 more source

Treatment ofClostridioides (Clostridium) difficileinfection

Annals of Medicine, 2019
Clostridioides (formerly: Clostridium) difficile infection (CDI) is a major cause of diarrhoea for inpatients as well as outpatients. Usually, CDI is healthcare-associated but the number of community-acquired infections is increasing. CDI is generally associated with changes in the normal intestinal microbiota caused by administration of antibiotics ...
Oksi Jarmo, Anttila Veli-Jukka, Mattila Eero   +2 more
openaire   +4 more sources

Microbe–microbe interactions during Clostridioides difficile infection

Current Opinion in Microbiology, 2020
Clostridioides difficile is the leading cause of hospital-acquired gastrointestinal infections and a major public health burden in the United States. C. difficile infection causes a spectrum of disease from mild diarrhea to severe complications such as pseudomembranous colitis, toxic megacolon and death.
Arwa Abbas, Joseph P Zackular
openaire   +3 more sources

Long‐term outcomes of children with ulcerative colitis after acute severe colitis: A GETAID pédiatrique multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet, Agathe Beauvais, Frank Ruemmele, Raphael Enaud, Thierry Lamireau, Rémi Duclaux‐Loras, Claire Dupont, Stéphanie Willot, Laure Bridoux‐Henno, Georges Dimitrov, Julie Lemale, Vincent Guinard‐Samuel, Valérie Bertrand, Anne Breton, Christine Martinez Vinson, Stéphanie Coopman, Delphine Ley, Bénédicte Pigneur, and the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du tube Digestif (GETAID) pédiatrique   +18 more
wiley   +1 more source

Fecal microbiota transplantation in a patient hospitalized in the intensive care unit – Case report

Heliyon
Clostridioides difficile infections are difficult and serious problem occurring in patients staying in intensive care units. In recent years, the number and severity of these infections, as well as the mortality rate, have been increasing, posing a ...
Katarzyna Oliwa-Libumska, Aleksandra Jaworska-Czerwinska, Malgorzata Mallek-Grabowska, Robert Wlodarski, Przemyslaw Zuratynski, Bartosz Kozlowski   +5 more
doaj   +1 more source

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

Gut Pathogens, 2021
Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C.
Seung Woo Ahn, Se Hee Lee, Uh Jin Kim, Hee-Chang Jang, Hak-Jong Choi, Hyon E. Choy, Seung Ji Kang, Seong Woon Roh   +7 more
doaj   +1 more source