Results 121 to 130 of about 20,312 (245)

Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano, Alice Caramaschi, Nadia Massa, Silvio Collani, Marta Mellai, Nadia Barizzone, Andrea Rocchetti, Paolo Bottino, Maria Simona Caroppo, Valeria Bonato, Rosanna Vaschetto, Sara Scaglione, Alessia Francese, Narges Gholami, Claudio Caria, Paola Bianchi, Cristiano Lauritano, Luigi Castello, Annalisa Roveta, Antonio Maconi, Stefano Andreoni, Sandra Dalfonso, Elisa Bona   +22 more
wiley   +1 more source

Re-establishing bile acid composition after treatment of recurrent Clostridioides difficile infection with fecal microbiota transplantation compared with oral vancomycin or a 12-strain bacterial mixture

Gut Microbes
Patients with Clostridioides difficile infection have high colonic levels of primary bile acids, which are potent germinators of Clostridioides difficile.
Anne Abildtrup Rode, Henri Duboc, Antonin Lamazière, Dominique Rainteau, Lydie Humbert, Emilie Gauliard, Mahtab Chehri, Andreas Munk Petersen, Morten Helms, Kristian Schønning, Henrik Vedel Nielsen, Peter Bytzer, Jørgen Engberg   +12 more
doaj   +1 more source

Production of Multiple Variants of the Antimicrobial Sactipeptide Gnavucin D by the Human Gut Isolate Mediterraneibacter gnavus HB038

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Gnavucin D, a novel antibacterial sactipeptide produced by Mediterraneibacter gnavus HB038, exhibits activity against multiple pathogens, including Clostridium perfringens, Streptococcus agalactiae, Bacillus cereus, and vancomycin‐resistant Enterococcus.
Mengfan Ding, Felipe Miceli de Farias, Paula M. O'Connor, Xiaohui Huang, Fiona C. Ross, Elaine C. Kennedy, Colin P. Hawkes, Colin Hill, Catherine Stanton, Reynolds Paul Ross   +9 more
wiley   +1 more source

Hospital‐Associated Antimicrobial Resistant Bacteria on 95 Mobile Phones: An International Metagenomic “Phonome” Analysis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Adrian Goldsworthy, Matthew Olsen, Nchafatso G. Obonyo, Peter Jones, Simon McKirdy, Abiola Senok, Rashed Alghafri, Rose Ghemrawi, Reem Almheiri, Oystein Tronstad, Jacky Y. Suen, John F. Fraser, Lotti Tajouri   +12 more
wiley   +1 more source

The Role of Clostridioides difficile Within the One Health Framework: A Review

Microorganisms
Clostridioides difficile is the leading cause of antibiotic-associated diarrhea in hospitalized patients. In recent years, the incidence of C. difficile infection (CDI) has increased globally, with a notable rise in community-associated CDI (CA-CDI). The
Sotiris Alexiou, Anastasia Diakou, Melania Kachrimanidou   +2 more
doaj   +1 more source

Recurrence of Clostridioides difficile infection and mortality in older inpatients

Purpose The prevalence of Clostridioides difficile infection in older and frail population is extremely high and adverse outcomes, including future recurrences and premature mortality, are common. Nonetheless, the clinical risk profile for Clostridioides
Volpato, Stefano, Cultrera, Rosario, Govoni, Benedetta, Mattioli, Irene, Zurlo, Amedeo, De Giorgio, Roberto, Remelli, Francesca   +6 more
core   +1 more source

Clostridioides difficile as a Zoonotic and Foodborne Pathogen: Reviewing the Global Evidence and South African Data

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Clostridioides difficile infections are increasingly problematic in areas with already burdened healthcare systems. From a One‐Health perspective, a lack of surveillance in developing countries greatly contributes to the limited information available on the zoonotic and foodborne potential of C. difficile.
M. Gouws, P. E. Strydom, D. Rip
wiley   +1 more source

Human Gut Phageome Analysis Uncovers Thousands of Highly Modular Endolysins

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Analysis of 9141 human gut metagenomes identified 15,267 phage genomes and 3794 highly modular endolysins. The recovered endolysins showed remarkable catalytic and cell wall–binding domain diversity, highlighting the gut phageome as a rich source of novel enzybiotics with therapeutic potential against multidrug‐resistant bacteria.
Raphael Kabir Niloy, Nurnabi Azad Jewel, Daniyal Karim, Mohimenul Haque Rolin, Tahsin Khan, Arzuba Akter, Shakhinur Islam Mondal   +6 more
wiley   +1 more source

Divergent Resilience of Bacterial and Fungal Gut Microbiota After Colorectal Surgery: Insights From a Prospective Longitudinal Cohort Study

MedComm, Volume 7, Issue 6, June 2026.
Patients undergoing colorectal surgery (n = 59) were sampled before and after surgery to investigate perioperative microbiome dynamics. Using 16S rRNA and ITS2 genes amplicon sequencing, bacterial diversity significantly decreased postoperatively, while fungal communities remained resilient.
Simon Wetzel, Eva Kohnert, Roman Huber, Alexander Müller, Agnes Knott, Lampros Kousoulas, Clemens Kreutz, Mohamed Tarek Badr, Ann‐Kathrin Lederer   +8 more
wiley   +1 more source

Clostridioides difficile Biofilm

Clostridioides difficile infection (CDI), previously Clostridium difficile infection, is a symptomatic infection of the large intestine caused by the spore-forming anaerobic, gram-positive bacterium Clostridioides difficile.
Vuotto, C., Buckley, A., Chilton, C., Donelli, G.   +3 more
core   +1 more source