Results 111 to 120 of about 1,730,491 (239)

Calprotectin and lactoferrin faecal levels in patients with Clostridium difficile infection (CDI): a prospective cohort study. [PDF]

, 2014
Measurement of both calprotectin and lactoferrin in faeces has successfully been used to discriminate between functional and inflammatory bowel conditions, but evidence is limited for Clostridium difficile infection (CDI).
Beadsworth, Mike B.J., Swale, Andrew, Mike B J Beadsworth, Munir Pirmohamed (40546), Andrew Swale, Kolamunnage-Dona, Ruwanthi, Chris M Parry, Little, Margaret, Hall, Amanda, Nick J. Beeching (623705), Parry, Chris M, Miyajima, Fabio, Paul Roberts (208537), Roberts, Paul, Fabio Miyajima, Amanda Hall, Ruwanthi Kolamunnage-Dona, Paul Roberts, Mike B. J. Beadsworth (623704), Pirmohamed, Munir, Chris M. Parry (304425), Beeching, Nick J, Munir Pirmohamed, Nick J Beeching, Beeching, Nicholas, Margaret Little (623703), Fabio Miyajima (208536), Andrew Swale (208539), Ruwanthi Kolamunnage-Dona (623706), Margaret Little, Parry, Christopher, Beadsworth, Mike BJ, Amanda Hall (210816)   +32 more
core   +1 more source

A Reassessment of Prophylactic Antibiotics in Low‐Infection‐Risk Electrophysiology Procedures

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Certain electrophysiology (EP) procedures are associated with minimal tissue disruption and do not involve permanent transvenous leads. As a result, these interventions carry a lower risk of device‐ or procedure‐related infection. These procedures include placement of implantable cardiac monitors, leadless pacemakers, and left atrial appendage
Rahel M. Sileshi, Katherine Mathes, Sathya Kosuri, Amulya Gupta, Neil Phillips, Rhea Pimentel, Martin Emert, Siva Soma, Rigoberto Ramirez, Raghuveer Dendi, Madhu Reddy, Seth H. Sheldon, Wissam El Atrouni, Larry M. Baddour, Amit Noheria   +14 more
wiley   +1 more source

Retrospective Study of the Epidemiology of Clostridioides difficile Infection in the Neurosurgery Department of a Tertiary Hospital in China

Infection and Drug Resistance, 2023
Xiajing Bi,1 Lisi Zheng,2 Zhi Yang,1 Tao Lv,2 Xiaofei Tong,1 Yunbo Chen2,3 1Department of Neurosurgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2State Key Laboratory for Diagnosis and ...
Bi X, Zheng L, Yang Z, Lv T, Tong X, Chen Y   +5 more
doaj  

Perioperative Prophylaxis in Pediatric Solid Organ Transplantation: A Baseline Stewardship Audit Using Routine Electronic Data

Transplant Infectious Disease, EarlyView.
Using routine electronic data from 164 pediatric transplants, we created reproducible stewardship measures of perioperative prophylaxis practice across transplant populations and protocol pathways. Starting prophylaxis was reliable, but continuation beyond intended stop targets—especially in abdominal transplantation—identified the clearest target for ...
Charles B. Foster, Kaitlyn Rivard, Venkatraman A. Arakoni, Blanca E. Gonzalez   +3 more
wiley   +1 more source

Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7

Cell Reports
Summary: The G protein-coupled receptors of the Frizzled (FZD) family, in particular FZD1,2,7, are receptors that are exploited by Clostridioides difficile toxin B (TcdB), the major virulence factor responsible for pathogenesis associated with ...
Julia Kinsolving, Julien Bous, Pawel Kozielewicz, Sara Košenina, Rawan Shekhani, Lukas Grätz, Geoffrey Masuyer, Yuankai Wang, Pål Stenmark, Min Dong, Gunnar Schulte   +10 more
doaj   +1 more source

Clinical Significance of Organ Preservation Fluid Cultures in Pediatric Abdominal Solid Organ Transplantation

Transplant Infectious Disease, EarlyView.
In this pediatric abdominal solid organ transplant cohort, preservation fluid‐related infections were rare but occurred in infant liver transplant recipients whose preservation fluid cultures grew pathogenic organisms. These findings suggest that routine bacterial preservation fluid cultures may be most useful for identifying clinically significant ...
Hassan A. Jamal, Yong K. Kwon, Pamela L. Valentino, Jodi M. Smith, Patrick J. Healey, Zheyi Teoh   +5 more
wiley   +1 more source

Cost-effectiveness analysis of fidaxomicin versus vancomycin in Clostridium difficile infection [PDF]

, 2014
OBJECTIVES: Fidaxomicin was non-inferior to vancomycin with respect to clinical cure rates in the treatment of Clostridium difficile infections (CDIs) in two Phase III trials, but was associated with significantly fewer recurrences than vancomycin.
Cornely, Oliver A., Odufowora-Sita, Olatunji, Van Engen, Anke K., Odeyemi, Isaac A. O., Retsa, Peny, Nathwani, Dilip   +5 more
core   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 871-889, October 2026.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li, Yong Zhang, Kaishuang Cai, Shaojun Deng, Chaofeng Tan, Yunjie Li, Wenjin Liang   +6 more
wiley   +1 more source

Transfusion‐associated graft‐vs‐host disease after liver transplantation presenting with rash and pancytopenia

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Irene Rivera‐Ruiz, César Guijarro‐Sánchez, Pedro J. Gómez‐Arias, Rafael Sánchez‐Sánchez, Manuel Galán‐Gutiérrez, Antonio José Vélez García‐Nieto   +5 more
wiley   +1 more source