Results 21 to 30 of about 1,849,474 (227)

Clostridioides difficile infection: are the three currently used antibiotic treatment options equal from pharmacological and microbiological points of view?

open access: yesInternational Journal of Infectious Diseases, 2022
Recently, the recommendations for the treatment of Clostridioides difficile infection (CDI) have been updated. However, in addition to the clinical efficacy data, the drug of choice should ideally represent optimal antimicrobial stewardship, with an ...
Marcela Krutova, Mark Wilcox, Ed Kuijper
doaj   +1 more source

Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective, Observational Study of Hospitalized Patients

open access: yesActa Médica Portuguesa, 2022
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cláudia Nazareth   +14 more
doaj   +1 more source

IL-27 induces LL-37/CRAMP expression from intestinal epithelial cells: implications for immunotherapy of Clostridioides difficile infection

open access: yesGut Microbes, 2021
Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
doaj   +1 more source

Clostridioides difficile Infection [PDF]

open access: yesAnnals of Internal Medicine, 2018
Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection.
Alice Y, Guh, Preeta K, Kutty
openaire   +2 more sources

Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study [PDF]

open access: yes, 2021
Infecció per Clostridioides difficile; Mortalitat; Factors de riscInfección por Clostridioides difficile; Mortalidad; Factores de riesgoClostridioides difficile infection; Mortality; Risk factorsWe aimed to describe the clinical presentation, treatment ...
Mizrahi, Assaf   +6 more
core   +1 more source

Update on Treatment of Clostridioides difficile Infection [PDF]

open access: yesMayo Clinic Proceedings, 2020
Clostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns.
Janice M. Cho   +2 more
openaire   +2 more sources

ANTIDEPRESSANT MEDICATIONS ARE ASSOCIATED WITH INCREASED RISK OF HOSPITAL-ACQUIRED CLOSTRIDIOIDES DIFFICILE INFECTION: A POPULATION-BASED STUDY [PDF]

open access: yesArquivos de Gastroenterologia, 2023
Background: During the past decade, Clostridioides difficile infection (CDI) has become the most common cause of antibiotic-associated diarrhea. Several risk factors have been implicated.
Antoine BOUSTANY   +4 more
doaj   +1 more source

Opportunities for Nanomedicine in Clostridioides difficile Infection [PDF]

open access: yesAntibiotics, 2021
Clostridioides difficile, a spore-forming bacterium, is a nosocomial infectious pathogen which can be found in animals as well. Although various antibiotics and disinfectants were developed, C. difficile infection (CDI) remains a serious health problem. C.
Pei-Wen Wang   +3 more
openaire   +3 more sources

Phage therapy for Clostridioides difficile infection

open access: yesFrontiers in Immunology, 2022
Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is responsible for many healthcare-associated infections, such as nosocomial diarrhea following antibiotic treatment. Importantly, there have been cases of unsuccessful treatment and relapse related to the emergence of highly virulent strains of C.
Kosuke Fujimoto   +3 more
openaire   +3 more sources

Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults

open access: yesSAGE Open Medicine, 2020
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12 
Kathryn A Connor, Kelly M Conn
doaj   +1 more source

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