Results 21 to 30 of about 20,312 (245)

Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective, Observational Study of Hospitalized Patients

Acta Médica Portuguesa, 2022
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cláudia Nazareth, Inês Leitão, Ernestina Reis, Hugo Inácio, Filomena Martins, Elmano Ramalheira, Flávia Cunha, Carla Santos, Sara Lino, Hugo Moreira, Nadiya Kruptsala, Andrea Santos, Laura Paixão, Leonor Pássaro, Mónica Oleastro   +14 more
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European Society of Clinical Microbiology and Infectious Diseases:2021 update on the treatment guidance document for Clostridioides difficile infection in adults [PDF]

, 2021
SCOPE: In 2009, the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) published the first treatment guidance document for Clostridioides difficile infection (CDI). This document was updated in 2014.
Guery, B., Wilcox, M.H., Hristea, A, Goorhuis, A, Tschudin-Sutter, S, Kuijper, E J, Coia, J; id_orcid, Bouza, E, van Rossen, T.M., Wilcox, M H, Allerberger, F, Vehreschild, M, Bouza, E., van Rossen, T M, Reigadas, E, van Prehn, J, Scharvik Olesen, B R, Norén, T., Allerberger, F., Ooijevaar, R.E., Scharvik Olesen, B.R., Burns, K, Ooijevaar, R E, van Prehn, J., Burns, K., Tschudin-Sutter, S., Krutova, M, Vogelzang, E.H., Hristea, A., Goorhuis, A., Fitzpatrick, F., Coia, J.E., Guery, B, Vehreschild, MJGT, Norén, T, Fitzpatrick, F, Krutova, M., Vogelzang, E H, Reigadas, E., Kuijper, E.J.   +39 more
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Clostridioides difficile Infection [PDF]

Annals of Internal Medicine, 2018
Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection.
Alice Y, Guh, Preeta K, Kutty
openaire   +2 more sources

Update on Treatment of Clostridioides difficile Infection [PDF]

Mayo Clinic Proceedings, 2020
Clostridioides difficile infection (CDI) is the leading cause of health care-associated infections in the United States. The increasing incidence and recurrence rates of CDI together with its associated morbidity and mortality are great concerns.
Janice M. Cho, Darrell S. Pardi, Sahil Khanna   +2 more
openaire   +2 more sources

ANTIDEPRESSANT MEDICATIONS ARE ASSOCIATED WITH INCREASED RISK OF HOSPITAL-ACQUIRED CLOSTRIDIOIDES DIFFICILE INFECTION: A POPULATION-BASED STUDY [PDF]

Arquivos de Gastroenterologia, 2023
Background: During the past decade, Clostridioides difficile infection (CDI) has become the most common cause of antibiotic-associated diarrhea. Several risk factors have been implicated.
Antoine BOUSTANY, Somtochukwu ONWUZO, Hadi Khaled Abou ZEID, Ashraf ALMOMANI, Imad ASAAD   +4 more
doaj   +1 more source

Analysis of the impact of secondary prophylaxis on recurrence in critically ill adults

SAGE Open Medicine, 2020
Introduction: Clostridioides (formerly Clostridium ) difficile infection recurrence in patients re-exposed to antibiotics for treatment of a non- Clostridioides difficile infection is high at approximately 33%. Low-dose per os vancomycin (e.g. 125 mg q12 
Kathryn A Connor, Kelly M Conn
doaj   +1 more source

Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism

Nature Communications, 2022
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. Here the authors engineer probiotics to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis ...
Elvin Koh, In Young Hwang, Hui Ling Lee, Ryan De Sotto, Jonathan Wei Jie Lee, Yung Seng Lee, John C. March, Matthew Wook Chang   +7 more
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Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection

, 2023
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical efficacy are incompletely understood.
Seekatz, Anna M., Karen Wong, Tanya M. Monaghan, Dina Kao, Abbas Yadegar, Wong, Karen, Laura Cook, Walter, Jens, Ali Nabavi-Rad, Anna M. Seekatz, Kao, Dina, Monaghan, Tanya M., Cook, Laura, Jens Walter, Nabavi-Rad, Ali, Ibrahim, Fathima F., Pakpoor, Sepideh F., Sepideh Pakpoor, Fathima F. Ibrahim, Yadegar, Abbas   +19 more
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An Integrated Pipeline For Prediction of Clostridioides Difficile Infection [PDF]

Scientific Reports, 2022
Abstract With the expansion of electronic health records(EHR)-linked genomic data comes the development of machine learning-enable models. There is a pressing need to develop robust pipelines to evaluate performance of integrated models and minimize systemic bias. We developed a prediction model of symptomatic Clostridioides difficile infection(
Jiang Li, Durgesh Chaudhary, Vaibhav Sharma, Vishakha Sharma, Venkatesh Avula, Paddy Ssentongo, Donna M. Wolk, Ramin Zand, Vida Abedi   +8 more
openaire   +3 more sources

Epidemiology of Clostridioides difficile Infections in Germany, 2010–2019: A Review from Four Public Databases

Infectious Diseases and Therapy, 2023
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich, Frederick J. Angulo, Fabian K. Berger, Christian Brösamle, Stefan Hagel, Andreas Leischker, Christoph Lübbert, Friederike Maechler, Sophie-Susann Merbecks, Nadia Minarovic, Jennifer C. Moïsi, Lutz von Müller, Phillip A. Reuken, Thomas Weinke, Holly Yu, Alexander Mellmann   +15 more
doaj   +1 more source