Results 281 to 290 of about 31,421 (293)
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Healthcare associated diarrhea, not Clostridioides difficile
Current Opinion in Infectious Diseases, 2020Purpose of review The aim of this article is to review the epidemiology, cause, diagnostic evaluation, and management of healthcare-associated diarrhea (HCAD) with particular attention to current epidemiology and recent developments in diagnostics.
Jennifer L. Saullo +2 more
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Clostridioides difficile Sporulation
Some members of the Firmicutes phylum, including many members of the human gut microbiota, are able to differentiate a dormant and highly resistant cell type, the endospore (hereinafter spore for simplicity). Spore-formers can colonize virtually any habitat and, because of their resistance to a wide variety of physical and chemical insults, spores can ...Mónica, Serrano +2 more
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Clostridioides difficile Biofilm
Clostridioides difficile infection (CDI), previously Clostridium difficile infection, is a symptomatic infection of the large intestine caused by the spore-forming anaerobic, gram-positive bacterium Clostridioides difficile. CDI is an important healthcare-associated disease worldwide, characterized by high levels of recurrence, morbidity, and mortality.Claudia, Vuotto +3 more
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Clostridioides difficile: diagnosis and treatments
BMJ, 2019AbstractClostridioides difficile(formerlyClostridium) is a major cause of healthcare associated diarrhea, and is increasingly present in the community. Historically,C difficileinfection was considered easy to diagnose and treat. Over the past two decades, however, diagnostic techniques have changed in line with a greater understanding of the ...
Frédéric Barbut +2 more
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Clostridioides difficile and Norovirus
2019Clostridioides difficile and norovirus are common causes of healthcare-associated gastroenteritis and both organisms cause outbreaks in pediatric healthcare settings. The spores are resistant to routine environmental cleaning with detergents and can survive in the environment for months. C.
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Foodborne transmission of Clostridioides difficile
Current Opinion in Gastroenterology, 2020The epidemiology of Clostridioides difficile infection (CDI) is changing, with increasing rates of community-acquired infections. In light of recent advances in understanding C. difficile transmission networks with whole-genome sequencing, new routes of spread outside the hospital need to be considered.
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Microscopy methods for Clostridioides difficile
AnaerobeMicroscopic technologies including light and fluorescent, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and cryo-electron microscopy have been widely utilized to visualize Clostridioides difficile at the molecular, cellular, community, and structural biology level. This comprehensive review summarizes the microscopy tools (
Chenlin Hu, Kevin W. Garey
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Antibiotic Resistances of Clostridioides difficile
The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile infections (CDIs) are a matter of concern for public health. Antibiotic resistance plays an important role in driving C. difficile epidemiology.Patrizia, Spigaglia +2 more
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Comparative Genomics of Clostridioides difficile
Clostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of nosocomial diarrhoea in hospitals. The availability of large numbers of genome sequences, mainly due to the use of next-generation sequencing methods, has undoubtedly shown their immense advantages in the determination of C ...Sandra, Janezic +2 more
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