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On the Discovery of Clostridium botulinum

Journal of the History of the Neurosciences, 1999
A description is given of a food intoxication in 1895 at Ellezelles, a village in Belgium. As a result 3 persons died within a few days and others became seriously ill. A thorough investigation by E. van Ermengem led to the discovery of Clostridium botulinum and botulinum toxin.
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Bacteriophages of Clostridium botulinum

Canadian Journal of Microbiology, 1972
Temperate bacteriophages of diverse morphology were demonstrated by electron microscopy in toxigenic cultures of Clostridium botulinum. The 41 strains examined included 23 type E and multiple representatives of all other types. Cultures induced with mitomycin-C generally gave better yields, but phages were also demonstrable in untreated cultures.A ...
C. E. Dolman, Eva Chang
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Clostridium botulinum toxins

International Journal of Food Microbiology, 1990
Abstract Structure, activation, destruction, lethality, genesis, neurotoxic action and medical application of botulinal toxins are reviewed.
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Clostridium botulinum and Clostridium perfringens

2007
Clostridium is a diverse genus of Gram-positive, endospore-bearing obligate anaerobes that are widespread in the environment. This genus includes more than 100 species, and the overall range in the G+C content (22–55 mol%) reflects the enormous phylogenetic variation encompassed within this group.
Kathie Grant, Jim McLauchlin
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Clostridium botulinum

2013
Botulism is a severe neuroparalytic disease, caused by consumption of minute quantities of botulinum neurotoxin (BoNT) in a contaminated food, or by development of toxin by toxigenic spores in the intestine of susceptible infants and adults. The severity, onset time, and duration of botulism are largely dependent upon dose and BoNT type, and because of
Kristin M. Marshall, Kathleen A. Glass
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CLOSTRIDIUM | Detection of Neurotoxins of Clostridium botulinum

2014
Botulism is caused by an exotoxin produced by the sporeforming bacterium Clostridium botulinum. Of the seven different toxin types, A, B, and E are the types commonly implicated in foodborne outbreaks of botulism. Clostridium botulinum toxins are extremely potent neurotoxins and generally occur at low concentrations in implicated foods.
Notermans, S.H.W.   +2 more
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Pathogenicity of Clostridium Botulinum

Journal of Infectious Diseases, 1925
The pathogenicity of Clostridium botulinum has been the subject of much laboratory work with variable results. Botulism in man is unquestionably a true intoxication caused by the soluble toxin elaborated by CI. botulinum under saprophytic conditions. There is a possibility, however, that the organism itself may multiply and produce this toxin within ...
William A. Starin, Gail M. Dack
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