Case Reports in Gastrointestinal Medicine, 2021 Clostridium difficile infection usually results from long-term and irregular antibiotic intake. The high-risk individuals for this infection include the patients undergoing chemotherapy due to malignancy, immunocompromised patients, and hospitalized ...
Hossain Salehi, Amir Mohammad Salehi
doaj +1 more source
Assessment of the utility of repeat stool testing for Clostridium difficile stool toxin using enzyme immunoassay [PDF]
, 2015 The poor performance of toxin enzyme immunoassay (EIA) for laboratory testing for Clostridium difficile (C. difficile) infection (CDI) is well acknowledged. Guidelines published in recent years state that testing solely with EIA for detecting toxins A
Barbara, Christopher +2 more
core +1 more source
Modelling diverse sources of Clostridium difficile in the community: importance of animals, infants and asymptomatic carriers [PDF]
arXiv, 2018 Clostridium difficile infections (CDIs) affect patients in hospitals and in the community, but the relative importance of transmission in each setting is unknown. We developed a mathematical model of C. difficile transmission in a hospital and surrounding community that included infants, adults, and transmission from animal reservoirs.
arxiv
Fluid fragmentation from hospital toilets [PDF]
arXiv, 2013 Hospital-acquired infections represent significant health and financial burdens to society. Clostridium difficile (C. difficile) is a particularly challenging bacteria with the potential to cause severe diarrhea and death. One mode of transmission for C.
arxiv
Navigation and control of outcomes in a generalized Lotka-Volterra model of the microbiome [PDF]
arXiv, 2020 The generalized Lotka-Volterra (gLV) equations model the microbiome as a collection of interacting ecological species. Here we use a particular experimentally-derived gLV model of C. difficile infection (CDI) as a case study to generate methods that are applicable to generic gLV models.
arxiv
Microbiome-derived bile acids contribute to elevated antigenic response and bone erosion in rheumatoid arthritis [PDF]
arXiv, 2023 Rheumatoid arthritis (RA) is a chronic, disabling and incurable autoimmune disease. It has been widely recognized that gut microbial dysbiosis is an important contributor to the pathogenesis of RA, although distinct alterations in microbiota have been associated with this disease.
arxiv
iMeta, EarlyView.Schematic representation of the design. Tryptophan metabolism is enriched in serum metabolites and gut microbiota of centenarians, potentially contributing to healthy longevity. A key tryptophan metabolite 5‐methoxyindoleacetic acid (5‐MIAA) is linked to the Christensenellaceae R‐7 group and exhibits effects of delaying cell senescence, promoting ...
Xiaorou Qiu +16 more
wiley +1 more source
Recurrent Pseudomembranous Colitis in an Ovarian Cancer Patient Undergoing Carboplatin Chemotherapy
Case Reports in Obstetrics and Gynecology, 2016 Background. Diarrhea is a common problem in ovarian cancer patients undergoing chemotherapy and Clostridium difficile infection has been identified as a cause.
Valerie A. Allen +2 more
doaj +1 more source
Evidence for antibiotic induced Clostridium perfringens diarrhoea [PDF]
, 2001 Clostridium difficile is a well documented cause of antibiotic associated diarrhoea in hospitalised patients, but may account for only approximately 20% of all cases.
Modi, N., Wilcox, M.H.
core +1 more source
Bezlotoxumab for prevention of recurrent Clostridium difficile infection in patients at increased risk for recurrence [PDF]
, 2018 Background: Bezlotoxumab is a human monoclonal antibody against Clostridium difficile toxin B indicated to prevent C. difficile infection (CDI) recurrence (rCDI) in adults at high risk for rCDI. This post hoc analysis of pooled monocolonal antibodies for
Dorr, Mary Beth +12 more
core +2 more sources